EGF R antibody | C225
Human anti EGF Receptor (Cetuximab Biosimilar)
- Product Type
- Monoclonal Antibody
- EGF R
|Human Anti-EGF R Antibody, clone C225 is a research grade biosimilar of the monoclonal antibody drug cetuximab. This product is supplied in a research grade format, i.e. in PBS buffer with preservative, it is not manufactured or formulated in the same way as the therapeutic reference product. A preservative free version is available on request.
This product is a recombinant human IgG1 kappa antibody with variable regions from the therapeutic antibody cetuximab.
Human Anti-EGF R Antibody is for research use only. It is suitable as a reference standard in a pharmacokinetic (PK) bridging ELISA with anti-cetuximab antibodies, for example HCA220 and HCA221P. It can also be used as capture and detection reagent in an anti-drug antibody (ADA) bridging ELISA, with an anti-cetuximab antibody in IgG1 format as reference standard, for example HCA221.
Cetuximab (Erbitux) is a chimeric monoclonal antibody drug (IgG1/kappa) approved for treatment of KRAS wild-type metastatic colorectal cancers and squamous cell carcinoma of the head and neck. This therapeutic antibody is directed against EGFR and inhibits tumor cell proliferation by blocking the interaction of epidermal growth factor (EGF) with its receptor.
This product is NOT FOR THERAPEUTIC USE.
View a summary of supporting anti-cetuximab antibody products
- Target Species
- Product Form
- Human IgG1 (kappa) antibody - liquid
- Purified recombinant IgG prepared by affinity chromatography on Protein A from a mammalian cell line
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Proclin 300
- Human EGF R
- >98% by SDS PAGE
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|Description||Product Code||Applications||Pack Size||List Price||Your Price||Quantity|
|Hispec Assay Diluent||BUF049A||E IY||50 ml||Log in|
|List Price||Your Price|
|Description||Hispec Assay Diluent|
|LYNX Rapid HRP Antibody Conjugation Kit||LNK002P||CJ||3 Conjugations For 400µg Antibody||Log in|
|List Price||Your Price|
|Description||LYNX Rapid HRP Antibody Conjugation Kit|
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"View all Anti-Human Products
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