CPS1 antibody | RM395
Rabbit anti CPS1
- Product Type
- Monoclonal Antibody
- Clone
- RM395
- Isotype
- IgG
- Specificity
- CPS1
Rabbit anti CPS1 antibody recognizes carbamoyis a multidomain mitochondrial enzyme which l-phosphate synthase [ammonia], mitochondrial, also known as CPSase I. CPS1 is a multidomain mitochondrial enzyme which produces carbamoyl phosphate (CP) from ammonia and bicarbonate and initiates disposal of nitrogen (Kim et al. 2017). CPS1 is the rate-limiting enzyme in the first step of the urea cycle, and is crucial for correct human liver metabolism. It is involved with arginine and pyrimidine metabolism (Çeliktaş et al. 2017). CPS1 is involved with liver diseases such as hepatitis C (HCV) and hepatic fibrosis (Wu et al. 2020). It is expressed mostly in intestinal epithelial cells and liver cells, but also in many cancer types including liver, colorectal, stomach, cervical, and pancreatic cancer (Çeliktaş et al. 2017). Accordingly, CPS1 is involved with the occurrence and development of malignancies (Wu et al. 2020). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Expected from Sequence Rat Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from animal origin-free culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
1% Bovine Serum Albumin
50% Glycerol - Immunogen
- A peptide corresponding to the N-terminus of human CPS1 (Carbamoyl-Phosphate Synthase). This antibody may also react to mouse or rat CPS1, as predicted by immunogen homology.
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Paraffin | 1/100 | 1/200 | |
Western Blotting | 1/5000 | 1/10000 |
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Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg | Log in | |||
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Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml | Log in | |||
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Description | Sheep anti Rabbit IgG:RPE |
- UniProt
- P31327
- Entrez Gene
- CPS1
- GO Terms
- GO:0000050 urea cycle
- GO:0004087 carbamoyl-phosphate synthase (ammonia) activity
- GO:0005524 ATP binding
- GO:0005980 glycogen catabolic process
- GO:0006541 glutamine metabolic process
- GO:0045909 positive regulation of vasodilation
- GO:0019240 citrulline biosynthetic process
- GO:0019433 triglyceride catabolic process
- GO:0032496 response to lipopolysaccharide
- View More GO Terms
- GO:0042645 mitochondrial nucleoid
- GO:0046209 nitric oxide metabolic process
- GO:0070409 carbamoyl phosphate biosynthetic process
MCA6360
157623If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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