Rabbit anti CD66e antibody
recognizes carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5), also known as CEA.
CD66e is a fetal glycoprotein which is normally expressed by mucosal cells and is not usually highly expressed after birth. However, CD66e can be expressed in a number of disease states including colorectal cancer (CRC) (Hall et al. 2019
) and cancers of the breast, liver, stomach, and pancreas. It is therefore considered to be a classic tumor marker. A number of benign conditions can also lead to elevations in CD66e expression including hypothyroidism and pancreatitis, but expression level is generally lower than in cancer (Asad-Ur-Rahman and Saif 2016
). High Cd66e expression in the serum of patients with cancer is related to tumor deterioration and subclinical metastases (Wan et al. 2019
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from animal origin-free culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
1% Bovine Serum Albumin
- Native CD66e protein purified from human liver tissue
- Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
integral to plasma membrane
anchored to membrane
basolateral plasma membrane
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of CD66e antibody
|Immunohistology - Paraffin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Secondary Antibodies Available
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