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CD62L antibody | FMC46

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Anti Human CD62L Antibody, clone FMC46 thumbnail image 1 Anti Human CD62L Antibody, clone FMC46 thumbnail image 2 Anti Human CD62L Antibody, clone FMC46 thumbnail image 3 Anti Human CD62L Antibody, clone FMC46 thumbnail image 4 Anti Human CD62L Antibody, clone FMC46 thumbnail image 5 Anti Human CD62L Antibody, clone FMC46 thumbnail image 6 Anti Human CD62L Antibody, clone FMC46 thumbnail image 7 Anti Human CD62L Antibody, clone FMC46 thumbnail image 8 Anti Human CD62L Antibody, clone FMC46 thumbnail image 9 Anti Human CD62L Antibody, clone FMC46 thumbnail image 10 Anti Human CD62L Antibody, clone FMC46 thumbnail image 11 Anti Human CD62L Antibody, clone FMC46 thumbnail image 12 Anti Human CD62L Antibody, clone FMC46 thumbnail image 13 Anti Human CD62L Antibody, clone FMC46 thumbnail image 14 Anti Human CD62L Antibody, clone FMC46 thumbnail image 15 Anti Human CD62L Antibody, clone FMC46 thumbnail image 16 Anti Human CD62L Antibody, clone FMC46 thumbnail image 17 Anti Human CD62L Antibody, clone FMC46 thumbnail image 18 Anti Human CD62L Antibody, clone FMC46 thumbnail image 19 Anti Human CD62L Antibody, clone FMC46 thumbnail image 20 Anti Human CD62L Antibody, clone FMC46 thumbnail image 21 Anti Human CD62L Antibody, clone FMC46 thumbnail image 22 Anti Human CD62L Antibody, clone FMC46 thumbnail image 23 Anti Human CD62L Antibody, clone FMC46 thumbnail image 24 Anti Human CD62L Antibody, clone FMC46 thumbnail image 25 Anti Human CD62L Antibody, clone FMC46 thumbnail image 26 Anti Human CD62L Antibody, clone FMC46 thumbnail image 27 Anti Human CD62L Antibody, clone FMC46 thumbnail image 28 Anti Human CD62L Antibody, clone FMC46 thumbnail image 29 Anti Human CD62L Antibody, clone FMC46 thumbnail image 30 Anti Human CD62L Antibody, clone FMC46 thumbnail image 31 Anti Human CD62L Antibody, clone FMC46 thumbnail image 32 Anti Human CD62L Antibody, clone FMC46 thumbnail image 33
Anti Human CD62L Antibody, clone FMC46 gallery image 1
Figure A. Alexa Fluor 488 conjugated Mouse anti Human CD3 (MCA463A488) and Alexa Fluor 700 conjugated Mouse IgG2b isotype control (MCA691A700). Figure B. Alexa Fluor 488 conjugated Mouse anti Human CD3 (MCA463A488) and Alexa Fluor 700 conjugated Mouse anti Human CD62L (MCA1076A700). All experiments performed on red cell lysed human blood gated on live lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer
Anti Human CD62L Antibody, clone FMC46 gallery image 2
Figure A. Alexa Fluor 488 conjugated Mouse anti Human CD3 (MCA463A488) and Pacific Blue conjugated Mouse IgG2b isotype control (MCA691PB). Figure B. Alexa Fluor 488 conjugated Mouse anti Human CD3 (MCA463A488) and Pacific Blue conjugated Mouse anti Human CD62L (MCA1076PB). All experiments performed on red cell lysed human blood gated on live lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer
Anti Human CD62L Antibody, clone FMC46 gallery image 3
Formalin fixed, paraffin embedded human spleen section stained with Mouse Anti-Human CD62L antibody, clone MEL-14 (MCA1076G),followed by biotinylated anti-Mouse IgG and Streptavidin Alkaline Phosphatase (red). Nuclei were counterstained with hematoxylin.
Anti Human CD62L Antibody, clone FMC46 gallery image 4
Published customer image:
Fitc conjugated Mouse anti Human CD62L antibody, clone FMC46 (MCA1076F) used to evaluate CD62L expression levels on human neutrophils and monocytes by flow cytometry.
Image caption:
Effect of flexible ureterenoscopy on CD62L cell surface expression of neutrophils and monocytes. The points represent mean ± SD.

From: Hughes SF, Moyes AJ, Lamb RM, Ella-Tongwiis P, Snyper NYF, Shergill I.
The role of phagocytic leukocytes following flexible ureterenoscopy, for the treatment of kidney stones: an observational, clinical pilots-study.
Eur J Med Res. 2020 Dec 11;25(1):68.
doi: 10.1186/s40001-020-00466-7.
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Anti Human CD62L Antibody, clone FMC46 gallery image 5
Published customer image:
FITC conjugated Mouse anti Human CD62L antibody, clone FMC46 (MCA1076F) used to assess CD62L expression on bovine peripheral blood mononuclear cells by flow cytometry.
Image caption:
Induction of central memory Tp1+/CD8+ cells.
b A live example of pseudo color plots of CD44 and CD62L expression from total lymphocytes (left) and from Tp1+/CD8+-gated cells from one animal in group 1, 7 days post-MVA boost (right).

From:Svitek N, Saya R, Awino E, Munyao S, Muriuki R, Njoroge T, Pellé R, Ndiwa N, Poole J, Gilbert S, Nene V, Steinaa L.
An Ad/MVA vectored Theileria parva antigen induces schizont-specific CD8+ central memory T cells and confers partial protection against a lethal challenge.
NPJ Vaccines. 2018 Sep 11;3:35.
doi: 10.1038/s41541-018-0073-5..
This image is from an open access article distributed under terms of a Creative Commons Attribution License.
Anti Human CD62L Antibody, clone FMC46 gallery image 6
Figure A. StarBright Violet 515 conjugated Mouse anti Human CD3 (MCA463SBV515). Figure B StarBright Violet 515 conjugated Mouse anti Human CD3 (MCA463SBV515) and StarBright Blue 700 conjugated Mouse and Human CD62L (MCA1076SBB700). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 7
Figure A. Alexa Fluor 488 conjugated Mouse anti Human CD3 (MCA463A488). Figure B. Alexa Fluor 488 conjugated Mouse anti Human CD3 (MCA463A488) and StarBright Violet 515 conjugated Mouse anti Human CD62L (MCA1076SBV515). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 8
Figure A. StarBright Blue 700 conjugated Mouse anti Human CD3 (MCA463SBB700). Figure B. StarBright Blue 700 conjugated Mouse anti Human CD3 (MCA463SBB700) and StarBright Violet 440 conjugated Mouse anti Human CD62L (MCA1076SBV440). All experiments performed on red blood cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 9
Figure A. Alexa Fluor 488 conjugated Mouse anti human CD3 (MCA463A488). Figure B. Alexa Fluor 488 conjugated Mouse anti human CD3 (MCA463A488) and StarBright Violet 610 conjugated Mouse anti Human CD62L (MCA1076SBV610). All experiments performed on red blood lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 10
Figure A. StarBright Violet 440 conjugated Mouse anti Human CD3 (MCA463SBV440). Figure B. StarBright Violet 440 conjugated Mouse anti Human CD3 (MCA463SBV440) and StarBright Violet 570 conjugated Mouse anti Human CD62L (MCA1076SBV570). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 11
Figure A. Alexa Fluor 488 conjugated Mouse anti Human CD3 (MCA463A488). Figure B. Alexa Fluor 488 conjugated Mouse anti Human CD3 (MCA463A488) and StarBright Violet 710 conjugated Mouse anti Human CD62L (MCA1076SBV710). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 12
Figure A. FITC conjugated Mouse anti Human CD3 (MCA463F). Figure B. FITC conjugated Mouse anti Human CD3 (MCA463F) and StarBright Violet 790 conjugated Mouse anti Human CD62L (MCA1076SBV790). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 13
Figure A. Alexa Fluor 647 conjugated Mouse anti Human CD3 (MCA463A647). Figure B. Alexa Fluor 647 conjugated Mouse anti Human CD3 (MCA463A647) and StarBright Violet 475 conjugated Mouse anti Human CD62L (MCA1076SBV475). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 14
Figure A. StarBright Violet 515 conjugated Mouse anti Human CD3 (MCA463SBV515). Figure B. StarBright Violet 515 conjugated Mouse anti Human CD3 (MCA463SBV515) and StarBright UltraViolet 400 conjugated Mouse anti Human CD62L (MCA1076SBUV400). All experiments performed on red cell lysed human blood gated on live lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 15
Figure A. StarBright Violet 400 conjugated Mouse anti Human CD3 (MCA463SBV440). Figure B. StarBright Violet 400 conjugated Mouse anti Human CD3 (MCA463SBV440) and StarBright Violet 760 conjugated Mouse anti Human CD62L (MCA1076SBV760). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 16
StarBright Violet 515 conjugated Mouse anti Human CD3 (MCA463SBV515). Figure B. StarBright Violet 515 conjugated Mouse anti Human CD3 (MCA463SBV515) and StarBright UltraViolet 665 conjugated Mouse anti Human CD62L (MCA1076SBUV665). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 17
Figure A. StarBright Violet 570 conjugated Mouse anti Human CD3 (MCA463SBV570). Figure B. StarBright Violet 570 conjugated Mouse anti Human CD3 (MCA463SBV570) and StarBright UltraViolet 445 conjugated Mouse anti Human CD62L (MCA1076SBUV445). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 18
Figure A. StarBright Violet 440 conjugated Mouse anti Human CD3 (MCA463SBV440). Figure B. StarBright Violet 440 conjugated Mouse anti Human CD3 (MCA463SBV440) and StarBright UltraViolet 795 conjugated Mouse anti human CD62L (MCA1076SBUV795). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 19
Figure A. StarBright Violet 570 conjugated Mouse anti Human CD3 (MCA463SBV570). Figure B StarBright Violet 570 conjugated Mouse anti Human CD3 (MCA463SBV570) and StarBright UltraViolet 510 conjugated Mouse anti human CD62L (MCA1076SBUV510). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 20
Figure A. StarBright Violet 790 conjugated Mouse anti Human CD3 (MCA463SBV790). Figure B. StarBright Violet 790 conjugated Mouse anti Human CD3 (MCA463SBV790). and StarBright UltraViolet 575 conjugated Mouse anti Human CD62L (MCA1076SBUV575). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 21
Figure A. Alexa Fluor 488 conjugated Mouse anti Human CD3 (MCA463A488). Figure B. Alexa Fluor 488 conjugated Mouse anti Human CD3 (MCA463A488) and StarBright UltraViolet 605 conjugated Mouse anti human CD62L (MCA1076SBUV605). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 22
Figure A. StarBright Violet 710 conjugated Mouse anti Human CD3 (MCA463SBV710). Figure B. StarBright Violet 710 conjugated Mouse anti Human CD3 (MCA463SBV710) and StarBright Blue 580 conjugated Mouse anti Human CD62L (MCA1076SBB580). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 23
Figure A. StarBright UltraViolet 795 conjugated Mouse anti Human CD3 (MCA463SBUV795). Figure B. StarBright UltraViolet 795 conjugated Mouse anti Human CD3 (MCA463SBUV795) and StarBright Blue 615 conjugated Mouse anti Human CD62L (MCA1076SBB615). All experiments performed on red cell lysed human blood gated on live lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 24
Figure A. StarBright Violet 515 conjugated Mouse anti Human CD3 (MCA463SBV610). Figure B. StarBright Violet 515 conjugated Mouse anti Human CD3 (MCA463SBV610) and StarBright Blue 765 conjugated Mouse anti Human CD62L (MCA1076SBB765). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 25
Figure A. StarBright Violet 515 conjugated Mouse anti Human CD3 (MCA463SBV515). Figure B. StarBright Violet 515 conjugated Mouse anti Human CD3 (MCA463SBV515) and StarBright Blue 765 conjugated Mouse anti Human CD62L (MCA1076SBB765). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 26
Figure A. StarBright Ultra Violet 400 conjugated Mouse anti Human CD3 (MCA463SBUV400). Figure B. StarBright Ultra Violet 400 conjugated Mouse anti Human CD3 (MCA463SBUV400) and StarBright Blue 810 conjugated Mouse anti Human CD62L (MCA1076SBB810). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 27
Figure A. StarBright UltraViolet 510 conjugated Mouse anti Human CD3 (MCA463SBUV510). Figure B. StarBright UltraViolet 510 conjugated Mouse anti Human CD3 (MCA463SBUV510) and StarBright Blue 675 conjugated Mouse anti Human CD62L (MCA1076SBB675). All experiments performed on red cell lysed human blood gated on live lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 28
Figure A. StarBright Blue 765 conjugated Mouse anti Human CD3 (MCA463SBB765). Figure B. StarBright Blue 765 conjugated Mouse anti Human CD3 (MCA463SBB765) and StarBright Yellow 575 conjugated Mouse anti Human CD62L (MCA1076SBY575). All experiments performed on red cell lysed Human blood gated on live single cell lymphocytes, in the presence of 10% Human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 29
Figure A. StarBright Violet 515 conjugated Mouse anti Human CD3 (MCA463SBV515). Figure B. StarBright Violet 515 conjugated Mouse anti Human CD3 (MCA463SBV515) and StarBright Yellow 720 conjugated Mouse anti Human CD62L (MCA1076SBY720). All experiments performed on human blood gated on live single lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 30
Figure A. StarBright Violet 475 conjugated Mouse anti Human CD3 (MCA463SBV475). Figure B. StarBright Violet 475 conjugated Mouse anti Human CD3 (MCA463SBV475) and StarBright Yellow 605 conjugated Mouse anti Human CD62L (MCA1076SBY605). All experiments performed on human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 31
Figure A. StarBright Violet 610 conjugated Mouse anti Human CD3(MCA463SBV610). Figure B. StarBright Violet 610 conjugated Mouse anti Human CD3 (MCA463SBV610) and StarBright Yellow 665 conjugated Mouse anti Human CD62L (MCA1076SBY665). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 32
Figure A. StarBright Violet 670 conjugated Mouse anti Human CD3 (MCA463SBV670). Figure B. StarBright Violet 670 conjugated Mouse anti Human CD3 (MCA463SBV670) and StarBright Yellow 800 conjugated Mouse anti Human CD62L (MCA1076SBY800). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.
Anti Human CD62L Antibody, clone FMC46 gallery image 33
Figure A. StarBright Violet 610 conjugated Mouse anti Human CD3 (MCA463SBV610). Figure B. StarBright Violet 610 conjugated Mouse anti Human CD3 (MCA463SBV610) and StarBright Red 775 conjugated Mouse anti Human CD62L (MCA1076SBR775). All experiments performed on red cell lysed human blood gated on live single cell lymphocytes, in the presence of 10% human serum. Data acquired on the ZE5 Cell Analyzer.

Mouse anti Human CD62L:StarBright Blue 580

Product Type
Monoclonal Antibody
Clone
FMC46
Isotype
IgG2b
Specificity
CD62L

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MCA1076SBB580
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F 100 Tests/0.5ml loader
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Mouse anti Human CD62L antibody, clone FMC46 recognizes human CD62L, also known a L-selectin, a 74-95 kDa member of the selectin family of adhesion receptors, which acts as a ligand for both CD62P (P-selectin) and CD62E (E-selectin). Human CD62L is constitutively expressed on most leucocytes including monocytes, granulocytes, lymphocytes, NK cells, bone marrow myeloid progenitor cells and on a subset of thymocytes.

CD62L plays an important role in leucocyte tethering and rolling on the endothelial cell surface and for the homing of naïve lymphocytes to lymph nodes and Peyers patches via HEV. Neutrophils require a constant supply of this molecule on the cell surface for migration into peripheral tissues and adhesion to activated endothelium at sites of inflammation, where CD62L is rapidly shed as soluble L-selectin, but surface expression still remains.

The expression of CD62L is down regulated on lymphocytes and neutrophils by PMA stimulation.

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Bovine
Cynomolgus monkey
Rhesus Monkey
Dog
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG conjugated to StarBright Blue 580 - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% sodium azide (NaN3)
1% bovine serum albumin
0.1% Pluronic F68
0.1% PEG 3350
0.05% Tween 20
Immunogen
PHA stimulated lymphoblasts
Fusion Partners
Spleen cells from immunized BALB/c mice were fused with cells of the mouse NS1 myeloma cell line
Max Ex/Em
Fluorophore Excitation Max (nm) Emission Max (nm)
StarBright Blue 580 475 582
Regulatory
For research purposes only
Guarantee
12 months from date of despatch
Acknowledgements
This product is covered by U.S. Patent No. 10,150,841 and related U.S. and foreign counterparts

Store at +4°C.
DO NOT FREEZE.
This product should be stored undiluted.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Flow Cytometry Neat
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Flow Cytometry
Use 5μl of the suggested working dilution to label 106 cells in 100μl. Best practices suggest a 5 minutes centrifugation at 6,000g prior to sample application.

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Source Reference

  1. Pilarski, L.M. et al. (1991) FMC46, a cell protrusion-associated leukocyte adhesion molecule-1 epitope on human lymphocytes and thymocytes.
    J Immunol. 147 (1): 136-43.

References for CD62L antibody

  1. Zola, H. et al. (1991) The expression of sub-population markers on B cells: a re-evaluation using high-sensitivity fluorescence flow cytometry.
    Dis Markers. 9 (2): 103-18.
  2. Sopp, P. & Howard, C.J. (1997) Cross-reactivity of monoclonal antibodies to defined human leucocyte differentiation antigens with bovine cells.
    Vet Immunol Immunopathol. 56 (1-2): 11-25.
  3. Haanstra, K.G. et al. (2008) Characterization of naturally occurring CD4+CD25+ regulatory T cells in rhesus monkeys.
    Transplantation 85:1185-92.
  4. Dalli, J. et al. (2008) Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles.
    Blood. 112 (6): 2512-9.
  5. Raposo, R.A. et al. (2011) Protein Kinase C and NF-{kappa}B-Dependent CD4 Downregulation in Macrophages Induced by T Cell-Derived Soluble Factors: Consequences for HIV-1 Infection.
    J Immunol. 187: 748-59.
  6. Hughes, S.F. et al. (2010) Total hip and knee replacement surgery results in changes in leukocyte and endothelial markers.
    J Inflamm (Lond). 7:2.
  7. Bismarck, D. et al. (2012) Canine CD4+CD8+ double positive T cells in peripheral blood have features of activated T cells.
    Vet Immunol Immunopathol. 149: 157-66.
  8. Hartley, A.N. & Tarleton, R.L. (2015) Chemokine receptor 7 (CCR7)-expression and IFNγ production define vaccine-specific canine T-cell subsets.
    Vet Immunol Immunopathol. 164 (3-4): 127-36.
    9. View The Latest Product References
  9. Hayhoe, R.P. et al. (2006) Annexin 1 and its bioactive peptide inhibit neutrophil-endothelium interactions under flow: indication of distinct receptor involvement.
    Blood. 107 (5): 2123-30.
  10. Urquhart, P. et al. (2007) Carbon monoxide-releasing molecules modulate leukocyte-endothelial interactions under flow.
    J Pharmacol Exp Ther. 321 (2): 656-62.
  11. Aspinall, A.I. et al. (2010) CX(3)CR1 and vascular adhesion protein-1-dependent recruitment of CD16(+) monocytes across human liver sinusoidal endothelium.
    Hepatology. 51 (6): 2030-9.
  12. Rothe, K. et al. (2017) Canine peripheral blood CD4+CD8+ double-positive Tcell subpopulations exhibit distinct Tcell phenotypes and effector functions.
    Vet Immunol Immunopathol. 185: 48-56.
  13. Withers, S.S. et al. (2018) Multi-color flow cytometry for evaluating age-related changes in memory lymphocyte subsets in dogs.
    Dev Comp Immunol. 87: 64-74.
  14. Hughes, S.F. et al. (2020) The role of phagocytic leukocytes following flexible ureterenoscopy, for the treatment of kidney stones: an observational, clinical pilots-study.
    Eur J Med Res. 25 (1): 68.
  15. Svitek, N. et al. (2018) An Ad/MVA vectored Theileria parva antigen induces schizont-specific CD8+ central memory T cells and confers partial protection against a lethal challenge.
    NPJ Vaccines. 3: 35.
  16. Tucker, N. et al. (2023) Bovine blood and milk T-cell subsets in distinct states of activation and differentiation during subclinical Staphylococcus aureus mastitis.
    J Reprod Immunol. 156: 103826.
  17. Yamauchi, A. et al. (2023) Negative Influence of Aging on Differentiation and Proliferation of CD8(+) T-Cells in Dogs.
    Vet Sci. 10 (9): 541

Flow Cytometry

Synonyms
LECAM-1
L-SELECTIN
UniProt
P14151
Entrez Gene
SELL
GO Terms
GO:0007596 blood coagulation
GO:0007155 cell adhesion
GO:0005887 integral to plasma membrane
GO:0005529 sugar binding
GO:0008201 heparin binding
GO:0043208 glycosphingolipid binding
GO:0050776 regulation of immune response
GO:0050900 leukocyte migration

MCA1076SBB580

100006952

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