Catenin Beta 1 antibody | RM276


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WB P ResetRabbit anti Catenin Beta 1
- Product Type
- Monoclonal Antibody
- Clone
- RM276
- Isotype
- IgG
- Specificity
- Catenin Beta 1
Rabbit anti Human catenin beta 1 antibody recognizes catenin beta-1, also known as beta-catenin, CTNNB1. Catenin beta 1 is a multifunctional protein with an important role in physiological homeostasis. The main regulator of catenin beta is the protein Wnt, an interaction central to the Wnt/beta-catenin signaling pathway (Shang et al. 2017). During embryogenesis, Wnt/beta-catenin signaling is involved with cell polarity, proliferation, and fate, and mutations in this signaling pathway are linked to birth defects (MacDonald et al. 2009). In adult tissue, appropriate Wnt/beta-catenin signaling is important for maintaining cellular processes involved with development, differentiation, and tissue homeostasis. Wnt/beta-catenin signaling dysregulation is implicated in numerous malignancies, and is involved with immune evasion during cancer (Pai et al. 2017). |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography of Protein A from animal origin-free culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
1% Bovine Serum Albumin
50% Glycerol - Immunogen
- A peptide corresponding to Human catenin beta 1
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Immunohistology - Paraffin | ![]() |
1/500 | 1/1000 |
Western Blotting | ![]() |
1/400 | 1/1000 |
Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
---|---|---|---|---|---|---|---|
Goat anti Rabbit IgG (Fc):Biotin | STAR121B | E WB | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):Biotin | ||||||
Goat anti Rabbit IgG (Fc):FITC | STAR121F | F | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):FITC | ||||||
Goat anti Rabbit IgG (Fc):HRP | STAR121P | E WB | 1 mg |
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Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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Description | Sheep anti Rabbit IgG:RPE |
- UniProt
- P35222
- Entrez Gene
- CTNNB1
- GO Terms
- GO:0000122 negative regulation of transcription from RNA polymerase II promoter
- GO:0005515 protein binding
- GO:0000578 embryonic axis specification
- GO:0001569 patterning of blood vessels
- GO:0001658 branching involved in ureteric bud morphogenesis
- GO:0001702 gastrulation with mouth forming second
- GO:0001711 endodermal cell fate commitment
- GO:0001837 epithelial to mesenchymal transition
- GO:0001889 liver development
- View More GO Terms
- GO:0003136 negative regulation of heart induction by canonical Wnt receptor signaling pathway
- GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis
- GO:0003704 specific RNA polymerase II transcription factor activity
- GO:0003713 transcription coactivator activity
- GO:0004871 signal transducer activity
- GO:0005198 structural molecule activity
- GO:0005667 transcription factor complex
- GO:0005813 centrosome
- GO:0005915 zonula adherens
- GO:0005916 fascia adherens
- GO:0005924 cell-substrate adherens junction
- GO:0005938 cell cortex
- GO:0006921 cellular component disassembly involved in apoptosis
- GO:0007016 cytoskeletal anchoring at plasma membrane
- GO:0007160 cell-matrix adhesion
- GO:0007268 synaptic transmission
- GO:0007398 ectoderm development
- GO:0007403 glial cell fate determination
- GO:0008022 protein C-terminus binding
- GO:0008285 negative regulation of cell proliferation
- GO:0042493 response to drug
- GO:0009898 internal side of plasma membrane
- GO:0009950 dorsal/ventral axis specification
- GO:0009954 proximal/distal pattern formation
- GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter
- GO:0010843 promoter binding
- GO:0010909 positive regulation of heparan sulfate proteoglycan biosynthetic process
- GO:0014010 Schwann cell proliferation
- GO:0016328 lateral plasma membrane
- GO:0016337 cell-cell adhesion
- GO:0016342 catenin complex
- GO:0016564 transcription repressor activity
- GO:0019901 protein kinase binding
- GO:0019903 protein phosphatase binding
- GO:0022009 central nervous system vasculogenesis
- GO:0030018 Z disc
- GO:0030027 lamellipodium
- GO:0030057 desmosome
- GO:0030331 estrogen receptor binding
- GO:0030521 androgen receptor signaling pathway
- GO:0030539 male genitalia development
- GO:0030902 hindbrain development
- GO:0030997 regulation of centriole-centriole cohesion
- GO:0031016 pancreas development
- GO:0031069 hair follicle morphogenesis
- GO:0031528 microvillus membrane
- GO:0032331 negative regulation of chondrocyte differentiation
- GO:0032355 response to estradiol stimulus
- GO:0032993 protein-DNA complex
- GO:0033077 T cell differentiation in thymus
- GO:0034333 adherens junction assembly
- GO:0034394 protein localization at cell surface
- GO:0034742 APC-Axin-1-beta-catenin complex
- GO:0034747 Axin-APC-beta-catenin-GSK3B complex
- GO:0042129 regulation of T cell proliferation
- GO:0042153 RPTP-like protein binding
- GO:0042475 odontogenesis of dentine-containing tooth
- GO:0043065 positive regulation of apoptosis
- GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB cascade
- GO:0043198 dendritic shaft
- GO:0043410 positive regulation of MAPKKK cascade
- GO:0043587 tongue morphogenesis
- GO:0044325 ion channel binding
- GO:0044334 canonical Wnt receptor signaling pathway involved in positive regulation of epithelial to mesenchymal transition
- GO:0044336 canonical Wnt receptor signaling pathway involved in negative regulation of apoptosis
- GO:0045202 synapse
- GO:0045294 alpha-catenin binding
- GO:0045296 cadherin binding
- GO:0045669 positive regulation of osteoblast differentiation
- GO:0045671 negative regulation of osteoclast differentiation
- GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway
- GO:0045765 regulation of angiogenesis
- GO:0045768 positive regulation of anti-apoptosis
- GO:0048145 regulation of fibroblast proliferation
- GO:0048262 determination of dorsal/ventral asymmetry
- GO:0048471 perinuclear region of cytoplasm
- GO:0048489 synaptic vesicle transport
- GO:0048538 thymus development
- GO:0048599 oocyte development
- GO:0048617 embryonic foregut morphogenesis
- GO:0048660 regulation of smooth muscle cell proliferation
- GO:0050681 androgen receptor binding
- GO:0050808 synapse organization
- GO:0051145 smooth muscle cell differentiation
- GO:0051149 positive regulation of muscle cell differentiation
- GO:0060440 trachea formation
- GO:0060479 lung cell differentiation
- GO:0060484 lung-associated mesenchyme development
- GO:0060492 lung induction
- GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development
- GO:0060789 hair follicle placode formation
- GO:0060916 mesenchymal cell proliferation involved in lung development
- GO:0061047 positive regulation of branching involved in lung morphogenesis
- GO:0061154 endothelial tube morphogenesis
- GO:0070369 beta-catenin-TCF7L2 complex
- GO:0070411 I-SMAD binding
- GO:0070412 R-SMAD binding
- GO:0070602 regulation of centromeric sister chromatid cohesion
- GO:0071363 cellular response to growth factor stimulus
- GO:0071681 cellular response to indole-3-methanol
- GO:0072033 renal vesicle formation
- GO:0072053 renal inner medulla development
- GO:0072054 renal outer medulla development
- GO:0072079 nephron tubule formation
- GO:0090279 regulation of calcium ion import
- GO:2000008 regulation of protein localization at cell surface
MCA6318

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