Acetyl Coa Carboxylase antibody | RM232

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Rabbit anti Acetyl Coa Carboxylase

Product Type
Monoclonal Antibody
Clone
RM232
Isotype
IgG
Product Code Applications Pack Size List Price Quantity
MCA6339
Datasheet
P WB
SDS
0.1 ml loader

Rabbit anti acetyl CoA carboxylase antibody recognizes acetyl CoA carboxylase, also known as ACC1 and ACACA.

Acetyl CoA carboxylase 1 is a lipogenic enzyme which catalyzes the carboxylation of acetyl CoA to malonyl CoA within fatty acid synthesis (Rios Garcia et al. 2017). This carboxylase activity is controlled by glucagon, epinephrine, and insulin, corresponding to the energy state of the organism. Acetyl CoA carboxylase is activated by phosphorylation and deactivated by dephosphorylation, allowing it to respond to energy status (Mabrouk et al. 1990). Acetyl CoA carboxylase appears to regulate the differentiation of CD4+ T cells, and has been suggested as a therapeutic target for a range of metabolic syndromes and cancers (Wang et al. 2019).

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Rat Expected from Sequence
Mouse Expected from Sequence
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein A from animal origin-free culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
1% Bovine Serum Albumin
50% Glycerol
Immunogen
A peptide corresponding to human acetyl CoA carboxylase 1

Storage Information

Storage
Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee
12 months from date of despatch

More Information

UniProt
Q13085
Entrez Gene
ACACA
Regulatory
For research purposes only

Applications of Acetyl Coa Carboxylase antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Immunohistology - Paraffin 1/300 1/500
Western Blotting 1/1000 1/2000
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (Fc):Biotin STAR121B E WB 1 mg loader
Goat anti Rabbit IgG (Fc):FITC STAR121F F 1 mg loader
Goat anti Rabbit IgG (Fc):HRP STAR121P E WB 1 mg loader
Goat anti Rabbit IgG (H/L):HRP STAR124P C E WB 1 mg loader
Sheep anti Rabbit IgG:FITC STAR34B C F 1 mg loader
Sheep anti Rabbit IgG:RPE STAR35A F 1 ml loader
Sheep anti Rabbit IgG:DyLight®488 STAR36D488GA F IF WB 0.1 mg
Sheep anti Rabbit IgG:DyLight®680 STAR36D680GA F IF WB 0.1 mg
Sheep anti Rabbit IgG:Dylight®800 STAR36D800GA F IF WB 0.1 mg

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