Acetyl Coa Carboxylase antibody | RM232
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WB P ResetRabbit anti Acetyl Coa Carboxylase
- Product Type
- Monoclonal Antibody
- Clone
- RM232
- Isotype
- IgG
- Specificity
- Acetyl Coa Carboxylase
Antibody Quality and Performance Guarantee
| Rabbit anti acetyl CoA carboxylase antibody recognizes acetyl CoA carboxylase, also known as ACC1 and ACACA. Acetyl CoA carboxylase 1 is a lipogenic enzyme which catalyzes the carboxylation of acetyl CoA to malonyl CoA within fatty acid synthesis (Rios Garcia et al. 2017). This carboxylase activity is controlled by glucagon, epinephrine, and insulin, corresponding to the energy state of the organism. Acetyl CoA carboxylase is activated by phosphorylation and deactivated by dephosphorylation, allowing it to respond to energy status (Mabrouk et al. 1990). Acetyl CoA carboxylase appears to regulate the differentiation of CD4+ T cells, and has been suggested as a therapeutic target for a range of metabolic syndromes and cancers (Wang et al. 2019). |
- Target Species
- Human
- Species Cross-Reactivity
-
Target Species Cross Reactivity Rat Expected from Sequence Mouse Expected from Sequence - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein A from animal origin-free culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
1% Bovine Serum Albumin
50% Glycerol - Immunogen
- A peptide corresponding to human acetyl CoA carboxylase 1
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at -20°C only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunohistology - Paraffin |  |
1/300 | 1/500 |
| Western Blotting | |
1/1000 | 1/2000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
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| Description | Goat anti Rabbit IgG (Fc):HRP | ||||||
| Goat anti Rabbit IgG (H/L):HRP | STAR124P | C E WB | 1 mg |
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| Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
| Sheep anti Rabbit IgG:FITC | STAR34B | C F | 1 mg |
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| Description | Sheep anti Rabbit IgG:FITC | ||||||
| Sheep anti Rabbit IgG:RPE | STAR35A | F | 1 ml |
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| Description | Sheep anti Rabbit IgG:RPE | ||||||
MCA6339
157602
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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