NFkB p105 (pSer907) Antibody

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NFkB p105 (pSer907) Antibody gallery image 1

Western blot analysis of extracts from HeLa cells untreated or treated with TNFa using Rabbit anti NFkB p105 (pSer907) antibody. Cells were cultured in serum free media for 16-20 hours before treatment with TNF-a (20ng/ml) for 30 minutes

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  • Rabbit anti NFkB p105 (pSer907)
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  • Product Type
    Polyclonal Antibody
  • Isotype
    Polyclonal IgG
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    AHP2658WBdatasheet pdfdatasheet pdf50 µl
    AHP2658
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
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    • Rabbit anti NFkB p105 (pSer907) antibody recognizes human nuclear factor NF-kappa-B (NFkB) p105 subunit, also known as DNA-binding factor KBF1, EBP-1 or nuclear factor of kappa light polypeptide gene enhancer in B-cells, when phosphorylated at serine 907.

      NFkB p105 is a large precursor protein that is cleaved at its C-terminus (which mainly contains ankyrin repeats) by the ubiquitin/proteasome pathway into the NFkB p50 subunit. The p50 subunit interacts with members of the Rel protein family to form transcription factors. The NFkB pathway plays a critical role in mediating immune responses after infection and has been implicated in a variety of diseases ranging from autoimmune disorders to cancer.

      NFkB is phosphorylated at serine 907 by GSK3-beta (Demarchi et al. 2003).
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      Western Blotting1/5001/2000

    • Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
      Due to the presence of phosphoproteins in milk, the use of milk based blocking reagents is not recommended. 1% BSA in PBS or TBS Tween should be used instead.
    • Instructions For Use

    Additional NFkB p105 (pSer907) Antibody Formats

    Formats Applications Sizes available
    NFkB p105 (pSer907) Antibody : Purified WB 50 µl
    • Copyright © 2017 Bio-Rad Antibodies (formerly AbD Serotec)

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      Recommended Negative Isotype Control

        Useful Reagents

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          Recommended Positive Controls

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              Further Reading

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