StarBright Dyes in Microfluidic Droplets
Encapsulating cells in droplets when paired with flow cytometry can enable precise functional analysis of cytokine secretion, antibody screening, and cytotoxicity assays at a single-cell level.
The Xdrop® instrument from Samplix is a microfluidic platform that generates single and double emulsion droplets. Read our latest application note in which the Xdrop single-cell cytotoxicity assay, combined with Bio-Rad StarBright™ Dye–conjugated fluorescent antibodies, enables precise profiling of CAR T cells.
Application Note: Droplet-Based Single-Cell Analysis Reveals Hidden CD4+ and CD8+ CAR T-Cell Cytotoxicity
Application Note: Droplet-Based Single-Cell Analysis Reveals Hidden CD4+ and CD8+ CAR T-Cell Cytotoxicity
Discover how Bio-Rad StarBright Dye–conjugated fluorescent antibodies expand the information obtainable by allowing precise profiling of CAR T cells when encapsulated in droplets.
They facilitate quantification of cytotoxic CD8+ CAR T cells and reveal distinct cytotoxic CD4+ CAR T cells in multicolor cell killing assays. Unlike bulk assays, this single-cell assay in droplets enables in-depth functional characterization of CAR T cells and CAR cassette construct designs.
Find out more about StarBright Dyes in other applications such as microscopy, flow cytometry, and western blot.
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StarBright Dyes
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StarBright Dye–Conjugated Antibodies
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StarBright Dyes — Collaboration
If you are interested in StarBright Dyes and have an idea for a collaborative project, simply complete our short form and a member of our team will respond.