Create mode – the default mode when you create a requisition and PunchOut to Bio-Rad. You can create and edit multiple shopping carts
Edit mode – allows you to edit or modify an existing requisition (prior to submitting). You will be able to modify only the cart that you have PunchedOut to, and won't have access to any other carts
Inspect mode – when you PunchOut to Bio-Rad from a previously created requisition but without initiating an Edit session, you will be in this mode. You cannot modify any Cart contents
Bio-Rad-Antibodies.com relies on third-party cookies to show you pricing, allow you to order online, and connect you to My Bio-Rad. Please amend your browser settings to enable third-party cookies and access this website’s full functionality.
Click here to find out how
Fc receptors are found on monocytes, macrophages, dendritic cells and B cells. As the name suggests they bind antibodies via their constant Fc domain rather than the antigen specific Fab domain.
This type of binding can lead to false positives and meaningless data. In order to prevent this type of binding, Fc blocking reagents (e.g. Human Fc Seroblock and Murine Fc Seroblock) have been developed which, when added to a staining protocol, can ensure that only antigen specific binding is observed.
Fig. 21. Fc blocking. THP-1 cells stained with mouse anti human CD11a (blue) or mouse IgG2a isotype control (MCA929F) (red) in the absence (A) and presence (B) of human Seroblock (BUF070A)