Native rabbit interferon gamma is a 167 amino acid cytokine with potent activating, anti-viral and anti-proliferative properties.
IFNγ is predominantly secreted by activated T lymphocytes in response to specific mitogens as a result of infection and has numerous immunological regulatory functions. Properties include macrophage and NK cell activation, upregulation of MHC class I and II molecules on various cells and induction of cytotoxicity.
- Target Species
- Product Form
- Purified recombinant protein - lyophilized
- Reconstitute with 20 μl sterile PBS containing 0.1% carrier protein
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
- Recombinant protein expressed in Pichia pastoris and purified by ion-exchange chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 10% Trehalose
- >95% by SDS PAGE analysis
- Protein Molecular Weight
- 16.9 kDa
- Prior to reconstitution store at -20oC.
After reconstitution store at -20oC.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
- GO:0009615 response to virus
- GO:0005125 cytokine activity
- GO:0005133 interferon-gamma receptor binding
- GO:0005615 extracellular space
- GO:0006955 immune response
- For research purposes only
Applications of IFN Gamma
|Application Name||Verified||Min Dilution||Max Dilution|
- This reagent may be used as a standard in a sandwich ELISA assay in conjunction with AHP2988 as a coating antibody and AHP2988B as a detection antibody.
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