This product is recombinant Plasmodium falciparum histidine rich protein-2, a member of the histidine rich protein family found in the malaria parasite. Histidine rich protein-2 is secreted by Plasmodium falciparum into the host erythrocyte cytosol and is expressed on the cell membrane or associated with the cytoskeleton of infected erythrocytes. Histidine rich protein-2 is thought to polymerise free haem to form haemozoin. It is also thought to play a role in the polymerisation of ferriprotoporphyrin IX, a by-product of haemoglobin degradation.
This protein contains a proprietary protein fusion partner.
- Product Form
- Purified recombinant protein - liquid
- Recombinant Plasmodium falciparum HRP2 expressed in Escherichia coli.
- Buffer Solution
- Sodium carbonate buffer, pH9.6
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- ~90% by SDS PAGE analysis
- Approx. Protein Concentrations
- Total protein concentration 1.0 mg/ml
- Protein Molecular Weight
- 37 kDa
- Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Plasmodium falciparum HRP2
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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