Prostate Specific Antigen
Filter by Application:SP Reset
|Native Human prostate specific antigen preparation is a purified form of human prostate-specific antigen (PSA), a glycoprotein of ~30 kDa found mainly in prostatic tissue and seminal fluid. PSA is also present in small quantities in the serum of normal men and is often elevated in the presence of prostate cancer and in other prostatic disorders.
Native Human prostate specific antigen demonstrates high specific activity and low levels of any contaminating proteins, including those with trypsin-like protease activity (Manning et al. 2012).
- Target Species
- Product Form
- Purified protein from human seminal fluid - liquid
- 7820-0604: Sterile filtered through a 0.2 µM membrane
- 7820-0504: Sterlie filtered through a 0.2 µM membrane
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- <0.1% Sodium Azide (NaN3)
- Pack Size: 0.2 mg>40% by SDS-PAGEPack Size: 0.1 mg>96% by SDS-PAGE
- Approx. Protein Concentrations
- 1.0 mg/ml
- Protein Molecular Weight
- 30 kDa
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the protein. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
References for Prostate Specific Antigen
Manning, M,L, et al. (2012) Trypsin-like proteolytic contamination of commercially available psa purified from human seminal fluid.
Prostate. 72 (11): 1233-8.
Arya, S.K. and Bhansali, S. (2012) Anti-Prostate Specific Antigen (Anti-PSA) Modified Interdigitated Microelectrode-Based Impedimetric Biosensor for PSA Detection
Biosensors Journal 1: H110601
Chornokur, G. et al. (2011) Impedance-Based Miniaturized Biosensor for Ultrasensitive and Fast Prostate-Specific Antigen Detection
Journal of Sensors, vol. 2011, Article ID 983752
Manning ML et al. (2013) Proteolysis of complement factors iC3b and C5 by the serine protease prostate-specific antigen in prostatic fluid and seminal plasma.
J Immunol. 190 (6): 2567-74.
Piletska, E.V. et al. (2014) Microplates with enhanced immobilization capabilities controlled by a magnetic field
J Chin Adv Mat Soc. 2: 118-29.
Isaacs, J.T. et al. (2018) SYNTHETIC ENHANCEMENT OF THE T-CELL ARMAMENTARIUM AS AN ANTI-CANCER THERAPY
US Patent application 20180148480 A1
Li, H. et al. (2020) Comprehensive role of prostate‐specific antigen identified with proteomic analysis in prostate cancer
J Cell Mol Med. 27 Jul. [Epub ahead of print].
Kostova, M.B. et al. (2018) PSA-alpha-2-macroglobulin complex is enzymatically active in the serum of patients with advanced prostate cancer and can degrade circulating peptide hormones.
Prostate. 78 (11): 819-29.
View The Latest Product References
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"View all Anti-Human Products
Always be the first to know.
When we launch new products and resources to help you achieve more in the lab.Yes, sign me up