Lactoferrin

Native Human Lactoferrin

Product Type
Purified Protein
Specificity
Lactoferrin

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PHP239
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Human lactoferrin is a ~78 kDa globular protein found in body secretions such as milk and saliva and is a member of the transferrin family proteins. Transferrins control the level of free iron in the body, by binding and transporting iron. Lactoferrin does not appear to have a transporting function, instead it has antimicrobial activity, by keeping the levels of iron in body fluids low and thus preventing microbes from acquiring iron. Removing free iron from body fluids and inflamed areas also serve to protect against the damaging effects of free radicals.

Lactoferrin is used as a therapeutic and prophylactic treatment of various illnesses, such as cancers and intestinal illnesses.

Target Species
Human
Product Form
Purified protein from human milk - lyophilized
Reconstitution
Reconstitute with 5 ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
Preparation
Purified by chromatography.
Preservative Stabilisers
None present
Purity
~ 90% by Biuret method
Regulatory
For research purposes only
Guarantee
12 months from date of despatch

Prior to reconstitution store at +4°C.
After reconstitution store at +4°C.
DO NOT FREEZE. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

References for Lactoferrin

  1. Wahl, A. et al. (2015) Breast Milk of HIV-Positive Mothers Has Potent and Species-Specific In Vivo HIV-Inhibitory Activity.
    J Virol. 89 (21): 10868-78.
  2. Yamashita, K. et al. (2017) Impact of a 7-Day Field Training on Oral Health Condition in Japan Ground Self-Defense Force Personnel.
    Mil Med. 182 (7): e1869-77.

Synonyms
Lactotransferrin
UniProt
P02788
Entrez Gene
LTF
View more products with Lactoferrin specificity

Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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