|Human lactoferrin is a ~78 kDa globular protein found in body secretions such as milk and saliva and is a member of the transferrin family proteins. Transferrins control the level of free iron in the body, by binding and transporting iron. Lactoferrin does not appear to have a transporting function, instead it has antimicrobial activity, by keeping the levels of iron in body fluids low and thus preventing microbes from acquiring iron. Removing free iron from body fluids and inflamed areas also serve to protect against the damaging effects of free radicals.
Lactoferrin is used as a therapeutic and prophylactic treatment of various illnesses, such as cancers and intestinal illnesses.
- Target Species
- Product Form
- Purified protein from human milk - lyophilized
- Reconstitute with 5 ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
- Purified by chromatography.
- Preservative Stabilisers
- None present
- ~ 90% by Biuret method
- For research purposes only
- 12 months from date of despatch
After reconstitution store at +4°C.
DO NOT FREEZE. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
|Application Name||Verified||Min Dilution||Max Dilution|
References for Lactoferrin
Wahl, A. et al. (2015) Breast Milk of HIV-Positive Mothers Has Potent and Species-Specific In Vivo HIV-Inhibitory Activity.
J Virol. 89 (21): 10868-78.
Yamashita, K. et al. (2017) Impact of a 7-Day Field Training on Oral Health Condition in Japan Ground Self-Defense Force Personnel.
Mil Med. 182 (7): e1869-77.
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