IL-11

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Recombinant Human Interleukin-11

Product Type: Recombinant Protein

Product Code	Applications	Pack Size	Your Price	List Price	Quantity
PHP048 Datasheet	FN SDS	10 µg	Log in		Get Quote

Summary
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Human Interleukin 11 is a potent lymphoid cell growth factor which stimulates the growth and survival of certain B cells and T cells. This product has an ED50 of 0.5ng/ml as determined in a proliferation assay using murine T1165 hybridoma cells.

Product Details

Target Species: Human
Product Form: Purified recombinant protein - lyophilized
Reconstitution: Reconstitute with 20ul distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
Preservative Stabilisers: None present
Carrier Free: Yes
Purity: >98% by SDS PAGE
Approx. Protein Concentrations: 0.5 mg/ml after reconstitution
Protein Molecular Weight: 19.5kDa (179 Amino acid sequence)

Storage Information

Storage: Prior to reconstitution store at -20^oC. Following reconstitution store at -20^oC. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Guarantee: Guaranteed for 3 months from the date of reconstitution or until the date of expiry, whichever comes first. Please see label for expiry date.

More Information

UniProt: P20809
Entrez Gene: IL11
GO Terms: GO:0005125 cytokine activity; GO:0005142 interleukin-11 receptor binding; GO:0005615 extracellular space; GO:0007267 cell-cell signaling; GO:0008083 growth factor activity; GO:0008284 positive regulation of cell proliferation; GO:0030168 platelet activation; GO:0030183 B cell differentiation; GO:0030219 megakaryocyte differentiation; GO:0033138 positive regulation of peptidyl-serine phosphorylation; GO:0043410 positive regulation of MAPKKK cascade; GO:0045444 fat cell differentiation; GO:0045944 positive regulation of transcription from RNA polymerase II promoter; GO:0046888 negative regulation of hormone secretion; GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
Regulatory: For research purposes only

Applications of IL-11

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Functional Assays		0.1ng/ml	10ng/ml

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

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