IL-11
No associated image currently available
Human Interleukin 11 is a potent lymphoid cell growth factor which stimulates the growth and survival of certain B cells and T cells. This product has an ED50 of 0.5ng/ml as determined in a proliferation assay using murine T1165 hybridoma cells.
Product Details
- Target Species
- Human
- Product Form
- Purified recombinant protein - lyophilised
- Reconstitution
- Reconstitute with 20ul distilled water. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
- Preservative Stabilisers
- None present
- Carrier Free
- Yes
- Purity
- >98% by SDS PAGE
- Approx. Protein Concentrations
- 0.5 mg/ml after reconstitution
- Protein Molecular Weight
- 19.5kDa (179 Amino acid sequence)
Storage Information
- Storage
- Prior to reconstitution store at -20oC. Following reconstitution store at -20oC. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
- Guarantee
- Guaranteed for 3 months from the date of reconstitution or until the date of expiry, whichever comes first. Please see label for expiry date.
More Information
- UniProt
- P20809
- Entrez Gene
- IL11
- GO Terms
- GO:0005125 cytokine activity
- GO:0005142 interleukin-11 receptor binding
- GO:0005615 extracellular space
- GO:0007267 cell-cell signaling
- GO:0008083 growth factor activity
- GO:0008284 positive regulation of cell proliferation
- GO:0030168 platelet activation
- GO:0030183 B cell differentiation
- GO:0030219 megakaryocyte differentiation
- GO:0033138 positive regulation of peptidyl-serine phosphorylation
- GO:0043410 positive regulation of MAPKKK cascade
- GO:0045444 fat cell differentiation
- GO:0045944 positive regulation of transcription from RNA polymerase II promoter
- GO:0046888 negative regulation of hormone secretion
- GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
- Regulatory
- For research purposes only
Applications of IL-11
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Functional Assays | 0.1ng/ml | 10ng/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Copyright © 2021 Bio-Rad Antibodies (formerly AbD Serotec)
Fluorescent Spectraviewer
Watch the Tool Tutorial Video ▸
How to Use the Spectraviewer?
Watch the Tool Tutorial Video ▸
- Start by selecting the application you are interested in, with the option to select an instrument from the drop down menu or create a customized instrument
- Select the fluorophores or fluorescent proteins you want to include in your panel to check compatibility
- Select the lasers and filters you wish to include
- Select combined or multi-laser view to visualize the spectra
