Native Human fibrinogen is a 340kDa glycoprotein involved in cell adhesion and migration processes including embryogenesis, metastasis, wound healing, blood coagulation and host immunity. It consists of a dimer, each part made up of three disulphide linked polypeptides known as the alpha, beta and gamma chains.
- Target Species
- Product Form
- Purified protein from human plasma - liquid
- Protein purified by precipitation
- Buffer Solution
- Citrate buffered saline
- Preservative Stabilisers
- None present
- 35-65% protein, of which >90% clottable protein.
Virtually free from plasminogen and plasmin.
- Approx. Protein Concentrations
- 1.25 mg/ml fibrinogen
- Protein Molecular Weight
- 340 kDa
- Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
- 12 months from date of despatch
- Entrez Gene
- GO Terms
protein binding, bridging
external side of plasma membrane
platelet alpha granule lumen
eukaryotic cell surface binding
response to calcium ion
- For research purposes only
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Applications of Fibrinogen
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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