Fibrinogen

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Native Human Fibrinogen

Product Type
Purified Protein
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
4440-8604 E FN 25 mg
Native Human fibrinogen is a 340kDa glycoprotein involved in cell adhesion and migration processes including embryogenesis, metastasis, wound healing, blood coagulation and host immunity. It consists of a dimer, each part made up of three disulphide linked polypeptides known as the alpha, beta and gamma chains.

Product Details

Target Species
Human
Product Form
Purified protein from human plasma - liquid
Preparation
Protein purified by precipitation
Buffer Solution
Citrate buffered saline
Preservative Stabilisers
None present
Purity
35-65% protein, of which >90% clottable protein.
Virtually free from plasminogen and plasmin.
Approx. Protein Concentrations
1.25 mg/ml fibrinogen
Protein Molecular Weight
340 kDa

Storage Information

Storage
Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
12 months from date of despatch

More Information

UniProt
P02671 Related reagents
P02675 Related reagents
P02679 Related reagents
Entrez Gene
FGA Related reagents
FGB Related reagents
FGG Related reagents
GO Terms
GO:0002576 platelet degranulation
GO:0030674 protein binding, bridging
GO:0005102 receptor binding
GO:0007165 signal transduction
GO:0005577 fibrinogen complex
GO:0009897 external side of plasma membrane
GO:0030168 platelet activation
GO:0031093 platelet alpha granule lumen
GO:0043499 eukaryotic cell surface binding
GO:0051258 protein polymerization
GO:0051592 response to calcium ion
GO:0051087 chaperone binding
GO:0005625 soluble fraction
Regulatory
For research purposes only

Applications of Fibrinogen

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Functional Assays
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.