Beta 2 Microglobulin
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Purified Human Beta 2 Microglobulin
- Product Type
- Purified Protein
- Specificity
- Beta 2 Microglobulin
Antibody Quality and Performance Guarantee
| native beta-2 microglobulin is a component of MHC class I molecules, which are present on all nucleated cells. Levels of beta-2 microglobulin can be used to assess renal function in kidney transplant recipients. Also known as B2M, it has been suggested that this protein can be used as a prognostic marker for HIV infection. |
- Target Species
- Human
- Product Form
- Human beta -2 microglobulin - lyophilized
- Reconstitution
- Reconstitute with 1.0ml sterile PBS
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution. - Preparation
- Human beta-2 microglobulin was prepared from urine from patients with renal tubular proteinuria.
- Preservative Stabilisers
- None present
- Purity
- >98% by SDS-PAGE
- Protein Molecular Weight
- 12 kDa
- Regulatory
- For research purposes only
- Guarantee
- Guaranteed for 3 months from the date of reconstitution or until the date of expiry, whichever comes first. Please see label for expiry date.
Store at +4oC. DO NOT FREEZE.
Should this product contain a precipitate we recommend microcentrifugation before use.
Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |  |
||
| Western Blotting | |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
References for Beta 2 Microglobulin
-
Miles, J.J. et al. (2018) Peptide mimic for influenza vaccination using nonnatural combinatorial chemistry.
J Clin Invest. 128 (4): 1569-80.
- UniProt
- P61769
- Entrez Gene
- B2M
- GO Terms
- GO:0000139 Golgi membrane
- GO:0005515 protein binding
- GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
- GO:0042612 MHC class I protein complex
- GO:0006955 immune response
- GO:0016032 viral reproduction
- GO:0031901 early endosome membrane
- GO:0050690 regulation of defense response to virus by virus
- GO:0060333 interferon-gamma-mediated signaling pathway
- View More GO Terms
View more products with BETA 2 MICROGLOBULIN specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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