Streptolysin-O

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Recombinant Streptolysin-O

Product Type
Recombinant Protein
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
PIP041 E 1 mg
Streptolysin O is a sulfhydryl-activated toxin produced by groups A, C and G of streptococci. It is an oxygen-labile hemolytic enzyme capable of causing lysis in animal cells, particularly white and red blood cells. It does so by binding to membrane cholesterol, where it polymerises to form a transmembrane channel.

Product Details

Target Species
Bacterial
Product Form
Recombinant purified Streptolysin O - liquid
Preparation
Recombinant Streptolysin O from transformed Escherichia coli. The preparation was purified by metal affinity chromatography.
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
None present
Activity
Total antigenic activity approx (internal indirect method): 7200 IU/ml
Specific antigenic activity approx: 2608 IU/mg of protein
Approx. Protein Concentrations
Total protein concentration 2.76 mg/ml.

Storage Information

Storage
Store at -70oC or -20oC for short term storage.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein.
Shelf Life
Please see label for expiry date

More Information

Regulatory
For research purposes only

Applications of Streptolysin-O

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.