Respiratory Syncytial Virus antibody

Goat anti Respiratory Syncytial Virus:Biotin
Goat anti Respiratory Syncytial Virus:HRP
Goat anti Respiratory Syncytial Virus
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|
7950-0104 | C E FN | 1 ml |
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7950-0304 | C E IF P | 1 ml |
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7950-0004 | C E FN* IF | 1 ml |
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RSV encodes three envelope glycoproteins, a small hydrophobic (SH) protein of unknown function, a glycoprotein (G) known as the attachment protein, and a fusion (F) protein. The F protein directs fusion of viral and cellular membranes, resulting in viral penetration, and can lead to the formation of syncytia.
The F protein is thought to be the principal antigen responsible for inducing an immune response.
Goat anti respiratory syncitial virus does not react with Parainfluenza 1-3, Influenza A and B, Adenovirus or uninfected HEp-2 or WI-38 cells. Goat anti respiratory syncitial virus polyclonal antibody is neutralizing and reacts well with bovine isolates.
Product Details
- Target Species
- Viral
- Product Form
- Purified IgG conjugated to Biotin - liquid
- Product Form
- Purified IgG conjugated to Horseradish Peroxidase (HRP) - liquid
- Product Form
- Purified IgG - liquid
- Buffer Solution
- Phosphate buffered saline
- Buffer Solution
- Phosphate buffered saline
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Preservative Stabilisers
0.002% Thiomersal 1% Bovine Serum Albumin - Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Immunogen
- Human RSV isolate.
- Approx. Protein Concentrations
- IgG concentration 4.0 mg/ml
- Approx. Protein Concentrations
- 1.0 mg/ml
- Approx. Protein Concentrations
- IgG concentration 4.0 mg/ml
Storage Information
- Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Storage
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
- Guarantee
- 12 months from date of despatch
- Guarantee
- 12 months from date of despatch
More Information
- Regulatory
- For research purposes only
Applications of Respiratory Syncytial Virus antibody
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
ELISA | |||
Functional Assays | |||
Immunohistology - Frozen | |||
ELISA | 1/200 | 1/1000 | |
Immunofluorescence | 1/20 | 1/200 | |
Immunohistology - Frozen | 1/20 | 1/200 | |
Immunohistology - Paraffin | |||
ELISA | |||
Functional Assays 1 | |||
Immunofluorescence | |||
Immunohistology - Frozen |
- 1This product contains sodium azide, removal by dialysis is recommended prior to use in functional assays.
Secondary Antibodies Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
Rabbit anti Goat IgG (Fc):HRP | STAR122P | C E WB | 1 mg |
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Rabbit anti Goat IgG (Fc):FITC | STAR122F | F | 1 mg |
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Useful Reagents Available
Description | Product Code | Applications | Pack Size | List Price | Quantity |
---|---|---|---|---|---|
TMB Signal+ | BUF054A | E | 100 ml | ||
TMB Core | BUF056A | E | 100 ml | ||
TMB Core+ | BUF062A | E | 100 ml | ||
AbGUARD® HRP Stabilizer Plus | BUF052A | C E P WB | 100 ml | ||
AbGUARD® HRP Stabilizer Plus | BUF052B | C E P WB | 500 ml | ||
AbGUARD® HRP Stabilizer Plus | BUF052C | C E P WB | 1000 ml |
Product Specific References
References for Respiratory Syncytial Virus antibody
-
Culley, F.J. et al. (2006) Role of CCL5 (RANTES) in viral lung disease.
J Virol. 80: 8151-7. -
Numata, M. et al. (2010) Pulmonary surfactant phosphatidylglycerol inhibits respiratory syncytial virus-induced inflammation and infection.
Proc Natl Acad Sci U S A. 107: 320-5. -
Roux, X. et al. (2008) Sub-nucleocapsid nanoparticles: a nasal vaccine against respiratory syncytial virus.
PLoS One. 3: e1766. -
Olszewska, W. et al. (2011) Antiviral and lung protective activity of a novel RSV fusion inhibitor in a mouse model.
Eur Respir J. 38: 401-8. -
Fonceca AM et al. (2012) Primary airway epithelial cultures from children are highly permissive to respiratory syncytial virus infection.
Thorax. 67 (1): 42-8. -
Ryzhakov, G. et al. (2011) IL-17 Boosts Proinflammatory Outcome of Antiviral Response in Human Cells.
J Immunol. 187: 5357-62. -
Fricke J et al. (2013) p38 and OGT sequestration into viral inclusion bodies in cells infected with human respiratory syncytial virus suppresses MK2 activities and stress granule assembly.
J Virol. 87 (3): 1333-47. -
Kipper, S. et al. (2015) New host factors important for respiratory syncytial virus (RSV) replication revealed by a novel microfluidics screen for interactors of matrix (M) protein.
Mol Cell Proteomics. 14 (3): 532-43. -
Russell, R.F. et al. (2015) Partial Attenuation of Respiratory Syncytial Virus with a Deletion of a Small Hydrophobic Gene Is Associated with Elevated Interleukin-1β Responses.
J Virol. 89 (17): 8974-81. -
Currie, S.M. et al. (2016) Cathelicidins Have Direct Antiviral Activity against Respiratory Syncytial Virus In Vitro and Protective Function In Vivo in Mice and Humans.
J Immunol. 196 (6): 2699-710. -
Kinnear, E. et al. (2017) Airway T cells protect against RSV infection in the absence of antibody.
Mucosal Immunol. May 24. [Epub ahead of print] -
Bajimaya, S. et al. (2017) Cholesterol is required for stability and infectivity of influenza A and respiratory syncytial viruses.
Virology. 510: 234-41. -
Choi, E.J. et al. (2018) Exchange Proteins Directly Activated by cAMP and Their Roles in Respiratory Syncytial Virus Infection.
J Virol. Sep 05 [Epub ahead of print].
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