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CGRP antibody

Goat anti Rat Calcitonin Gene-Related Peptide

Product Type
Polyclonal Antibody
Polyclonal IgG

Product Code Applications Pack Size List Price Your Price Qty
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
C E IF P 0.1 ml loader
List Price Your Price

Goat anti Rat Calcitonin Gene-Related Peptide antibody recognizes Calcitonin gene-related peptide, also known as CGRP, a neuropeptide that acts as a vasodilator and plays a role in in the pathophysiology of migraine (Recober & Russo 2009). Goat anti Rat Calcitonin Gene-Related Peptide antibody reacts with both the whole molecule (amino acids 1-37) and the C-terminal fragment (23-37).

Target Species
Species Cross-Reactivity
Target SpeciesCross Reactivity
Guinea Pig
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified Ig - liquid
Purified Ig prepared by affinity chromatography on Protein G
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09%Sodium Azide (NaN3)
Synthetic rat Tyr-CGRP (23-37) conjugated to gamma globulin.
Approx. Protein Concentrations
IgG concentration 5.0 mg/ml
For research purposes only
12 months from date of despatch

This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/500 1/2500
Immunohistology - Frozen
Immunohistology - Paraffin
Immunohistology - Resin
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Description Product Code Applications Pack Size List Price Your Price Quantity
Rabbit anti Goat IgG (Fc):FITC STAR122F F 1 mg loader
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Rabbit anti Goat IgG (Fc):HRP STAR122P C E WB 1 mg loader
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Description Rabbit anti Goat IgG (Fc):HRP

Description Product Code Applications Pack Size List Price Your Price Quantity
Antigen Retrieval Buffer, pH8.0 BUF025A P 500 ml
List Price Your Price
Description Antigen Retrieval Buffer, pH8.0

References for CGRP antibody

  1. Collins, J.J. et al. (2000) Distribution and origin of secretoneurin-immunoreactive nerves in the female rat uterus.
    Neuroscience. 95 (1): 255-64.
  2. Chetty, R. et al. (2006) Pancreatic endocrine tumour with ductules: further observations of an unusual histological subtype.
    Pathology. 38 (1): 5-9.
  3. Weir, K.A. and Lunam, C.A. (2006) Immunohistochemical study of cutaneous nerves in the emu.
    Cell Tissue Res. 326: 697-705.
  4. Brock, J.A. et al. (2007) Postnatal androgen deprivation dissociates the development of smooth muscle innervation from functional neurotransmission in mouse vas deferens.
    J Physiol. 581: 665-78.
  5. Marchant, N.J. et al. (2007) Coexpression of prodynorphin and corticotrophin-releasing hormone in the rat central amygdala: evidence of two distinct endogenous opioid systems in the lateral division.
    J Comp Neurol. 504: 702-15.
  6. Pitzer, C. et al. (2008) Granulocyte-colony stimulating factor improves outcome in a mouse model of amyotrophic lateral sclerosis.
    Brain. 131: 3335-47.
  7. Ikeda, E. et al. (2009) Fully functional bioengineered tooth replacement as an organ replacement therapy.
    Proc Natl Acad Sci U S A. 106: 13475-80.
  8. Iliff, J.J. et al. (2009) Epoxyeicosanoids as mediators of neurogenic vasodilation in cerebral vessels.
    Am J Physiol Heart Circ Physiol. 296: H1352-63.
  9. View The Latest Product References
  10. Yu, W.M. et al. (2009) Disruption of laminin in the peripheral nervous system impedes nonmyelinating Schwann cell development and impairs nociceptive sensory function.
    Glia. 57: 850-9.
  11. Golden, J.P. et al. (2010) RET signaling is required for survival and normal function of nonpeptidergic nociceptors.
    J Neurosci. 30: 3983-94.
  12. Iliff, J.J. et al. (2010) Epoxyeicosatrienoic acids are endogenous regulators of vasoactive neuropeptide release from trigeminal ganglion neurons.
    J Neurochem. 115: 1530-42.
  13. Fan, W. et al. (2010) Structural and cellular features in metaphyseal and diaphyseal periosteum of osteoporotic rats.
    J Mol Histol. 41: 51-60.
  14. Gnanamanickam, G.J. and Llewellyn-Smith, I.J. (2011) Innervation of the rat uterus at estrus: a study in full-thickness, immunoperoxidase-stained whole-mount preparations.
    J Comp Neurol. 519: 621-43.
  15. Tague, S.E. and Smith, P.G. (2011) Vitamin D receptor and enzyme expression in dorsal root ganglia of adult female rats: modulation by ovarian hormones.
    J Chem Neuroanat. 41: 1-12.
  16. Hamed, K. et al. (2011) Changes in cutaneous innervation in patients with chronic pain after burns.
    Burns. 37: 631-7
  17. Zou, M. et al. (2012) Brn3a/Pou4f1 regulates dorsal root ganglion sensory neuron specification and axonal projection into the spinal cord.
    Dev Biol. 364: 114-27.
  18. Zimmerman, A.L. et al. (2012) Monoaminergic Modulation of Spinal Viscero-Sympathetic Function in the Neonatal Mouse Thoracic Spinal Cord
    PLoS One. 7: e47213.
  19. Drummond, E.S. et al. (2014) Increased expression of cutaneous α1-adrenoceptors after chronic constriction injury in rats.
    J Pain. 15 (2): 188-96.
  20. Drummond, P.D. et al. (2014) Upregulation of α1-adrenoceptors on cutaneous nerve fibres after partial sciatic nerve ligation and in complex regional pain syndrome type II.
    Pain. 155: 606-16.
  21. Li, Z. et al. (2014) Activation of MrgC receptor inhibits N-type calcium channels in small-diameter primary sensory neurons in mice.
    Pain. 155 (8): 1613-21.
  22. Park, S.I. et al. (2015) Soft, stretchable, fully implantable miniaturized optoelectronic systems for wireless optogenetics.
    Nat Biotechnol. 33 (12): 1280-1286.
  23. O'Brien, D.E. et al. (2015) ERK2 Alone Drives Inflammatory Pain But Cooperates with ERK1 in Sensory Neuron Survival.
    J Neurosci. 35 (25): 9491-507.
  24. Vogelaar CF et al. (2015) Pharmacological Suppression of CNS Scarring by Deferoxamine Reduces Lesion Volume and Increases Regeneration in an In Vitro Model for Astroglial-Fibrotic Scarring and in Rat Spinal Cord Injury In Vivo.
    PLoS One. 10 (7): e0134371.
  25. Sheahan, T.D. et al. (2015) Voluntary Exercise Training: Analysis of Mice in Uninjured, Inflammatory, and Nerve-Injured Pain States.
    PLoS One. 10 (7): e0133191.
  26. Huang, A.Y. & Wu, S.Y. (2015) Calcitonin Gene-Related Peptide Reduces Taste-Evoked ATP Secretion from Mouse Taste Buds.
    J Neurosci. 35 (37): 12714-24.
  27. Watanabe, M. et al. (2015) Expression and Regulation of Cav3.2 T-Type Calcium Channels during Inflammatory Hyperalgesia in Mouse Dorsal Root Ganglion Neurons.
    PLoS One. 10 (5): e0127572.
  28. Chucair-Elliott, A.J. et al. (2015) Degeneration and regeneration of corneal nerves in response to HSV-1 infection.
    Invest Ophthalmol Vis Sci. 56 (2): 1097-107.
  29. Van Steenwinckel, J. et al. (2015) Stromal cell-derived CCL2 drives neuropathic pain states through myeloid cell infiltration in injured nerve.
    Brain Behav Immun. 45: 198-210.
  30. Payne, S.C. et al. (2015) Regeneration of sensory but not motor axons following visceral nerve injury.
    Exp Neurol. 266: 127-42.
  31. Valtcheva, M.V. et al. (2015) Enhanced nonpeptidergic intraepidermal fiber density and an expanded subset of chloroquine-responsive trigeminal neurons in a mouse model of dry skin itch.
    J Pain. 16 (4): 346-56.
  32. Chucair-Elliott, A.J. et al. (2015) Degeneration and regeneration of corneal nerves in response to HSV-1 infection.
    Invest Ophthalmol Vis Sci. 56 (2): 1097-107.
  33. Marvaldi L et al. (2015) Enhanced axon outgrowth and improved long-distance axon regeneration in sprouty2 deficient mice.
    Dev Neurobiol. 75 (3): 217-31.
  34. Wong, A.W. et al. (2015) Neurite outgrowth in normal and injured primary sensory neurons reveals different regulation by nerve growth factor (NGF) and artemin.
    Mol Cell Neurosci. 65: 125-34.
  35. Lin, S.H. et al. (2016) Evidence for the involvement of ASIC3 in sensory mechanotransduction in proprioceptors.
    Nat Commun. 7: 11460.
  36. Kim, Y.S. et al. (2016) Coupled Activation of Primary Sensory Neurons Contributes to Chronic Pain.
    Neuron. 91 (5): 1085-96.
  37. Takahashi, N. et al. (2016) Morphology of P2X3-immunoreactive nerve endings in the rat laryngeal mucosa.
    Histochem Cell Biol. 145 (2): 131-46.
  38. Takiguchi, M. et al. (2018) Neonatal spinal injury induces de novo projections of primary afferents to the lumbosacral intermediolateral nucleus in rats.
    IBRO Rep. 4: 1-6.
  39. Sun, Y. et al. (2020) Somatostatin neurons in the central amygdala mediate anxiety by disinhibition of the central sublenticular extended amygdala.
    Mol Psychiatry. Oct 01 [Epub ahead of print].
  40. Rytel, L. & Całka, J. (2020) Aspirin Administration Affects Neurochemical Characterization of Substance P-Like Immunoreactive (SP-LI) Nodose Ganglia Neurons Supplying the Porcine Stomach.
    Biomed Res Int. 2020: 1049179.
  41. Morellini, N. et al. (2020) Decreased neural expression of the noradrenaline transporter in the papillary dermis after partial sciatic nerve lesion.
    J Chem Neuroanat. 107: 101806.
  42. Lin, J.H. et al. (2021) ATF3-Expressing Large-Diameter Sensory Afferents at Acute Stage as Bio-Signatures of Persistent Pain Associated with Lumbar Radiculopathy.
    Cells. 10 (5): 992
  43. Godinho, M.J. et al. (2020) Regeneration of adult rat sensory and motor neuron axons through chimeric peroneal nerve grafts containing donor Schwann cells engineered to express different neurotrophic factors.
    Exp Neurol. 330: 113355.


Immunohistology - Paraffin

Entrez Gene
GO Terms
GO:0005576 extracellular region
GO:0005179 hormone activity


152223 156661 160791 160792 161056 161057 162260

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