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IgG2c antibody

Goat anti Mouse IgG2c:Alk. Phos.

Product Type
Polyclonal Antibody
Polyclonal IgG

Product Code Applications Pack Size List Price Your Price Qty
Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
E 0.5 mg loader
List Price Your Price

Goat anti Mouse IgG2c antibody recognizes mouse IgG2c, otherwise known as the Igh 1b allele of IgG2a. Goat anti Mouse IgG2c antibody is assessed by ELISA and immunoelectrophoresis and has been shown to react with IgG2c in C57BL/6, SJL, C57BL/10, CB20, C57BL/6 by Balb/C crosses and pools of serum of outbred mice and does not react with L-chains or other IgG subclasses.

Target Species
Product Form
Purified IgG conjugated to Alkaline Phosphatase - liquid
Purified IgG prepared by affinity chromatography.
Antiserum Preparation
Antisera to mouse IgG2c were raised by repeated immunisations of goats with highly purified antigen.
Buffer Solution
50mM HEPES, 0.1M Nacl, 1mM Mgcl2, 0.1mM Zncl2
Preservative Stabilisers
0.09%Sodium Azide
0.2%Bovine Serum Albumin
Native mouse IgG2c.
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml.
For research purposes only.
12 months from date of despatch.

Store at +4°C.
This product should be stored undiluted. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/1000 1/10000
Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.

References for IgG2c antibody

  1. Jalili, R.B. et al. (2010) Local Expression of Indoleamine 2,3 Dioxygenase in Syngeneic Fibroblasts Significantly Prolongs Survival of an Engineered Three-Dimensional Islet Allograft.
    Diabetes 59: 2219-27
  2. Arnold, I.C. et al. (2011) The C-terminally encoded, MHC class II-restricted T cell antigenicity of the Helicobacter pylori virulence factor CagA promotes gastric preneoplasia.
    J Immunol. 186: 6165-72.
  3. Zouggari, Y. et al. (2013) B lymphocytes trigger monocyte mobilization and impair heart function after acute myocardial infarction.
    Nat Med. 19 (10): 1273-80.
  4. Paes, W. et al. (2016) Recombinant polymorphic membrane protein D in combination with a novel, second-generation lipid adjuvant protects against intra-vaginal Chlamydia trachomatis infection in mice.
    Vaccine. 34 (35): 4123-31.
  5. Carroll, E.C. et al. (2016) The Vaccine Adjuvant Chitosan Promotes Cellular Immunity via DNA Sensor cGAS-STING-Dependent Induction of Type I Interferons.
    Immunity. 44 (3): 597-608.
  6. McEntee, C.P. et al. (2020) Type I IFN signalling is required for cationic adjuvant formulation (CAF)01-induced cellular immunity and mucosal priming.
    Vaccine. 38 (3): 635-43.
  7. Müller-Winkler, J. et al. (2021) Critical requirement for BCR, BAFF, and BAFFR in memory B cell survival.
    J Exp Med. 218 (2) [Epub ahead of print].
  8. Muñoz-Wolf, N. et al. (2023) Non-canonical inflammasome activation mediates the adjuvanticity of nanoparticles.
    Cell Rep Med. 4 (1): 100899.
  9. View The Latest Product References

Igh-1b Allele


160155 161010 161017 164717

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