Survivin antibody

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Goat anti Human Survivin (C-Terminal)

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
AHP2075 E WB 0.1 mg
Goat anti Human survivin antibody recognizes human Baculoviral IAP repeat-containing protein 5 also known as survivin, Apoptosis inhibitor 4 or Apoptosis inhibitor survivin. Survivin is a 142 amino acid ~18 kDa proteins playing roles in preventing apoptosis and in cell proliferation. Multiple isoforms of human survivin may be generated by alternative splicing. Goat anti Human survivin antibody is expected to recognize the canonical isoform 1 and also isoform 2. However, goat anti human survivin antibody is not expected to recognize isoforms 3 to 7 which all lack the immunogen sequence used to generate the antibody (UniProt :O15392).

Product Details

Target Species
Human
Product Form
Purified IgG - liquid
Antiserum Preparation
Antiserum to human Survivin (CT) was raised by repeated immunisation of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
Buffer Solution
TRIS buffered saline
Preservative Stabilisers
0.02% Sodium Azide (NaN3)
0.5% Bovine Serum Albumin
Immunogen
Synthetic peptide sequence CVRRAIEQLAAMD from the C-Terminal region of Survivin (NP_001159.2; NP_001012271.1).
Approx. Protein Concentrations
IgG concentration 0.5mg/ml

Storage Information

Storage
Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
Shelf Life
18 months from date of despatch.

More Information

UniProt
O15392 Related reagents
Entrez Gene
BIRC5 Related reagents
Regulatory
For research purposes only

Applications of Survivin antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA 1/16000
Western Blotting 0.01 0.5ug/ml
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Western Blotting
AHP2075 detects a band of approximately 18kDa in MOLT4 cell lysates.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Rabbit anti Goat IgG (Fc):FITC STAR122F 1 mg F
Rabbit anti Goat IgG (Fc):HRP STAR122P 1 mg C E WB