Snail antibody

Rabbit anti Snail

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
Snail

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VPA00571
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Rabbit anti Human SNAIL antibody recognizes SNAIL also known as zinc finger protein SNAI1, protein snail homolog 1, snail 1 homolog or snail 1 zinc finger protein.

The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by SNAI1 is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2 (provided by RefSeq, Jul 2008).

Rabbit anti Human SNAIL antibody detects a band of 29 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Anti SNAIL detects a band of approximately 29 kDa in Jurkat cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid.
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide (NaN3).
Immunogen
KLH conjugated synthetic peptide corresponding to amino acid 1-30 of human SNAIL
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20oC, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
O95863
Entrez Gene
SNAI1
GO Terms
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0001649 osteoblast differentiation
GO:0001707 mesoderm formation
GO:0001837 epithelial to mesenchymal transition
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0008270 zinc ion binding
GO:0010718 positive regulation of epithelial to mesenchymal transition
GO:0016563 transcription activator activity
GO:0019900 kinase binding
GO:0030335 positive regulation of cell migration
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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