In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA9 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. HOXA9 is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between HOXA9 and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between HOXA9 and the upstream homeobox A10 (HOXA10) gene (provided by RefSeq, Mar 2011).
Rabbit anti Human HOXA9 antibody detects a band of 30 kDa. The antibody has been extensively validated for western blotting using human liver tissue lysate.
- Target Species
- Western Blotting
- Rabbit anti HOXA9 detects a band of approximately 30 kDa in human liver tissue
- Product Form
- Purified IgG - liquid
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
1% Bovine Serum Albumin
- A partial Recombinant HOXA9 (amino acids 63-272)
- Instructions For Use
- Please refer to the PrecisionAb western blotting protocol. For additional information on secondary antibody dilution and exposure time see product web page.
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Shelf Life
- As supplied, 12 months from date of despatch.
- P31269 Related reagents
- Entrez Gene
- HOXA9 Related reagents
- GO Terms
- GO:0005515 protein binding
- GO:0003700 sequence-specific DNA binding transcription factor activity
- GO:0006355 regulation of transcription, DNA-dependent
- GO:0016563 transcription activator activity
- GO:0043565 sequence-specific DNA binding
- PrecisionAb™ is a trademark of Bio-Rad Laboratories.
- For research purposes only
Applications of HOXA9 antibody
|Application Name||Verified||Min Dilution||Max Dilution|
PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.
Secondary Antibodies Available
|Description||Product Code||Pack Size||Applications||List Price||Quantity|
|Goat anti Rabbit IgG (H/L):HRP||STAR208P||2 ml||WB|
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