HOXA9 antibody
Rabbit anti Human HOXA9 antibody recognizes homeobox protein Hox-A9, also known as homeobox protein Hox-1G.
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA9 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. HOXA9 is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between HOXA9 and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between HOXA9 and the upstream homeobox A10 (HOXA10) gene (provided by RefSeq, Mar 2011).
Rabbit anti Human HOXA9 antibody detects a band of 30 kDa. The antibody has been extensively validated for western blotting using human liver tissue lysate.
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA9 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. HOXA9 is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between HOXA9 and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between HOXA9 and the upstream homeobox A10 (HOXA10) gene (provided by RefSeq, Mar 2011).
Rabbit anti Human HOXA9 antibody detects a band of 30 kDa. The antibody has been extensively validated for western blotting using human liver tissue lysate.
Product Details
- Target Species
- Human
- Western Blotting
- Rabbit anti HOXA9 detects a band of approximately 30 kDa in human liver tissue
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
1% Bovine Serum Albumin - Immunogen
- A partial Recombinant HOXA9 (amino acids 63-272)
- Instructions For Use
- Please refer to the PrecisionAb western blotting protocol. For additional information on secondary antibody dilution and exposure time see product web page.
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Shelf Life
- As supplied, 12 months from date of despatch.
More Information
- UniProt
- P31269 Related reagents
- Entrez Gene
- HOXA9 Related reagents
- GO Terms
- GO:0005515 protein binding
- GO:0003700 sequence-specific DNA binding transcription factor activity
- GO:0006355 regulation of transcription, DNA-dependent
- GO:0016563 transcription activator activity
- GO:0043565 sequence-specific DNA binding
- Acknowledgements
- PrecisionAb™ is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of HOXA9 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.
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Secondary Antibodies Available
| Description | Product Code | Pack Size | Applications | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | 2 ml | WB |
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