hnRNP A2B1 antibody
Rabbit anti Human hnRNP A2B1 antibody recognizes the heterogeneous nuclear ribonucleoproteins A2/B1, also known as hnRNP A2 / hnRNP B1 and nuclear ribonucleoprotein particle A2 protein.
hnRNP A2B1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. HNRNPA2B1 has been described to generate two alternatively spliced transcript variants which encode different isoforms (provided by RefSeq, Jul 2008).
Rabbit anti Human hnRNP A2B1 antibody detects bands of 34-36 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
hnRNP A2B1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. HNRNPA2B1 has been described to generate two alternatively spliced transcript variants which encode different isoforms (provided by RefSeq, Jul 2008).
Rabbit anti Human hnRNP A2B1 antibody detects bands of 34-36 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti hnRNP A2B1 antibody recognizes a band of approximately 34-36 kDa in HeLa cell lysates
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography on immunogen
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
<50% Glycerol - Immunogen
- Recombinant protein of human hnRNP A2B1
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
Storage Information
- Storage
- Store undiluted at -20°C, avoiding repeated freeze thaw cycles
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P22626
- Entrez Gene
- HNRNPA2B1
- GO Terms
- GO:0000166 nucleotide binding
- GO:0005515 protein binding
- GO:0000398 nuclear mRNA splicing, via spliceosome
- GO:0003723 RNA binding
- GO:0005737 cytoplasm
- GO:0005654 nucleoplasm
- GO:0005681 spliceosomal complex
- GO:0005730 nucleolus
- GO:0030530 heterogeneous nuclear ribonucleoprotein complex
- GO:0043047 single-stranded telomeric DNA binding
- GO:0050658 RNA transport
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only
Applications of hnRNP A2B1 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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