HLA-DQA2 antibody

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Anti HLA-DQA2 Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with HLA-DQA2 antibody followed by detection with HRP conjugated Goat anti Rabbit IgG antibody (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 2 second exposure. Arrow points to HLA-DQA2 (molecular weight 28 kDa).

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Rabbit anti HLA-DQA2

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: HLA-DQA2

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VPA00443 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Rabbit anti Human HLA-DQA2 antibody recognizes the HLA class II histocompatibility antigen DQ alpha 2 chain, also known as DX alpha chain, HLA class II histocompatibility antigen, DQ (6) alpha chain or MHC class II DQA2.

HLA-DQA2 belongs to the HLA class II alpha chain family. The HLA-DQA2 gene encoded protein forms a heterodimer with a class II beta chain. It is located in intracellular vesicles and plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (B-cells, dendritic cells, macrophages) and are used to present antigenic peptides on the cell surface to be recognized by CD4 T-cells (provided by RefSeq, Jun 2010).

Rabbit anti Human HLA-DQA2 antibody detects a band of 28 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti HLA-DQA2 detects a band of approximately 28 kDa in Raji cell lysates.
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid.
Preparation: Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃).
Immunogen: KLH conjugated synthetic peptide corresponding to amino acid 39-66 of human HLA-DQA2
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Mouse

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: P01906
Entrez Gene: HLA-DQA2
GO Terms: GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II; GO:0042613 MHC class II protein complex; GO:0032395 MHC class II receptor activity; GO:0005887 integral to plasma membrane; GO:0005765 lysosomal membrane; GO:0005789 endoplasmic reticulum membrane; GO:0005794 Golgi apparatus; GO:0006955 immune response; GO:0010008 endosome membrane; View More GO Terms; GO:0031295 T cell costimulation; GO:0050852 T cell receptor signaling pathway; GO:0060333 interferon-gamma-mediated signaling pathway