Glucagon antibody

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Goat anti Glucagon (N-Terminal)

Product Type
Polyclonal Antibody
Isotype
Polyclonal IgG
Product Code Applications Pack Size List Price Quantity
4660-1140
Datasheet
E
SDS
1 ml

Goat anti Glucagon antibody recognizes the pancreatic polypeptide hormone glucagon, whose actions are antagonistic to insulin. Glucagon is produced by A cells within the Islets of Langerhans in the pancreas.

Tumors arising from glucagon producing cells are termed glucagonomas, and this antibody may be useful in identifying such tumours.

Product Details

Target Species
Human
Species Cross-Reactivity
Target SpeciesCross Reactivity
Pig
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Purified IgG prepared by affinity chromatography on Protein G
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Porcine glucagon, amino acids 1-12, conjugated with bovine thyroglobulin.
Approx. Protein Concentrations
IgG concentration 5.0 mg/ml

Storage Information

Storage
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.

Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Guarantee
12 months from date of despatch

More Information

UniProt
P01275
Entrez Gene
GCG
GO Terms
GO:0005886 plasma membrane
GO:0005576 extracellular region
GO:0005179 hormone activity
GO:0005625 soluble fraction
GO:0006112 energy reserve metabolic process
GO:0007186 G-protein coupled receptor protein signaling pathway
GO:0007631 feeding behavior
GO:0050796 regulation of insulin secretion
GO:0008283 cell proliferation
GO:0071377 cellular response to glucagon stimulus
Regulatory
For research purposes only

Applications of Glucagon antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
ELISA
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using the appropriate negative/positive controls.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Rabbit anti Goat IgG (Fc):FITC STAR122F F 1 mg loader
Rabbit anti Goat IgG (Fc):HRP STAR122P C E WB 1 mg loader

Product Specific References

References for Glucagon antibody

  1. Li, S. et al. (2010) SEL1L deficiency impairs growth and differentiation of pancreatic epithelial cells.
    BMC Dev Biol. 10: 19.

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