DPF2 antibody
Goat anti DPF2
- Product Type
- Polyclonal Antibody
- Isotype
- Polyclonal IgG
- Specificity
- DPF2
Antibody Quality and Performance Guarantee
| Goat anti DPF2 antibody recognizes zinc finger protein ubi-d4, also known as BAF45D, REQ, and UBID4. DPF2 is a plant homeodomain (PHD) finger protein with roles in apoptosis, noncanonical NF-kappaB signaling and oncogenesis (Liu et al. 2015). It acts as an adaptor protein, linking RelB/p52 with the SWI/SNF chromatin-remodeling complex (Shin et al. 2017). In human tissues, DPF2 is ubiquitously expressed but was discovered as being required for apoptosis in myeloid cells. Furthermore, this protein appears to play a role in inhibiting the differentiation of myeloid cells. DPF2 is associated with multiple human cancers including cervical cancer and acute myelogenous leukemia (AML) (Huber et al. 2017). DPF2 also appears to play a role in influenza infection, with knockdown of DPF2 leading to decreased infectivity of the virus (Shin et al. 2017). |
- Target Species
- Human
- Product Form
- Purified IgG - liquid
- Antiserum Preparation
- Antisera to human DPF2 were raised by repeated immunizations of goats with highly purified antigen. Purified IgG was prepared by affinity chromatography.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.02% Sodium Azide
0.5% Bovine Serum Albumin - Immunogen
- Peptide with sequence C-QPPTPVSQRSEEQKS, from the internal region of the protein sequence according to NP_006259.1
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
Store at -20°C only.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunohistology - Paraffin |  |
5 ug/ml | |
| Western Blotting | |
1 ug/ml | 3 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Western Blotting
- Goat anti Human DPF2 antibody detects a band of approximately 50 kDa and 48 kDa in cell lysates
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Rabbit anti Goat IgG (Fc):FITC | STAR122F | F | 1 mg |
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| List Price | Your Price | ||||||
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| Description | Rabbit anti Goat IgG (Fc):FITC | ||||||
| Rabbit anti Goat IgG (Fc):HRP | STAR122P | C E WB | 1 mg |
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| List Price | Your Price | ||||||
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| Description | Rabbit anti Goat IgG (Fc):HRP | ||||||
- UniProt
- Q92785
- Entrez Gene
- DPF2
- GO Terms
- GO:0003676 nucleic acid binding
- GO:0006915 apoptosis
- GO:0005634 nucleus
- GO:0005813 centrosome
- GO:0006350 transcription
- GO:0008270 zinc ion binding
- GO:0008624 induction of apoptosis by extracellular signals
- GO:0045449 regulation of transcription
AHP3020
158408
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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