Cytochrome P450 Aromatase antibody

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Anti Cytochrome P450 Aromatase Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with cytochrome P450 aromatase antibody followed by detection with Goat anti Rabbit HRP conjugated (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 299 second exposure. Arrow points to cytochrome P450 aromatase (molecular weight 58 kDa).

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Rabbit anti Cytochrome P450 Aromatase

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: Cytochrome P450 Aromatase

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Rabbit anti Human cytochrome P450 aromatase antibody recognizes cytochrome P450 aromatase, also known as CYP450 family 26 subfamily B member, cytochrome P450 retinoid metabolizing protein or cytochrome P450, family 26, subfamily B, polypeptide 1.

This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants (provided by RefSeq, Apr 2013).

Rabbit anti Human cytochrome P450 aromatase antibody detects a band of 58 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti cytochrome P450 aromatase antibody recognizes a band of approximately 58 kDa in HepG2 cell lysates.
Species Cross-Reactivity: Target Species Cross Reactivity

Rat; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Preparation: Rabbit polyclonal antibody purified by affinity chromatography on immunogen.
Buffer Solution: TRIS buffered glycine.
Preservative Stabilisers: 0.01% Thiomersal
<20% Glycerol
Immunogen: Recombinant protein encompassing a sequence within the center region of human cytochrome P450 aromatase
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Rat

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: Q9NR63
Entrez Gene: CYP26B1
GO Terms: GO:0009055 electron carrier activity; GO:0001709 cell fate determination; GO:0001972 retinoic acid binding; GO:0005789 endoplasmic reticulum membrane; GO:0005792 microsome; GO:0055114 oxidation-reduction process; GO:0006805 xenobiotic metabolic process; GO:0007140 male meiosis; GO:0007283 spermatogenesis; View More GO Terms; GO:0008401 retinoic acid 4-hydroxylase activity; GO:0009954 proximal/distal pattern formation; GO:0020037 heme binding; GO:0030326 embryonic limb morphogenesis; GO:0034653 retinoic acid catabolic process; GO:0048387 negative regulation of retinoic acid receptor signaling pathway