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Cytochrome P450 Aromatase antibody

Rabbit anti Cytochrome P450 Aromatase

Product Type
PrecisionAb Polyclonal
Polyclonal IgG
Cytochrome P450 Aromatase

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Datasheet Datasheet Datasheet
SDS Safety Datasheet SDS
WB 100 µl loader
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Rabbit anti Human cytochrome P450 aromatase antibody recognizes cytochrome P450 aromatase, also known as CYP450 family 26 subfamily B member, cytochrome P450 retinoid metabolizing protein or cytochrome P450, family 26, subfamily B, polypeptide 1.

This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants (provided by RefSeq, Apr 2013).

Rabbit anti Human cytochrome P450 aromatase antibody detects a band of 58 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Western Blotting
Anti cytochrome P450 aromatase antibody recognizes a band of approximately 58 kDa in HepG2 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Rabbit polyclonal antibody purified by affinity chromatography on immunogen.
Buffer Solution
TRIS buffered glycine.
Preservative Stabilisers
0.01% Thiomersal
<20% Glycerol
Recombinant protein encompassing a sequence within the center region of human cytochrome P450 aromatase
For research purposes only.
12 months from date of despatch.
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Entrez Gene
GO Terms
GO:0009055 electron carrier activity
GO:0001709 cell fate determination
GO:0001972 retinoic acid binding
GO:0005789 endoplasmic reticulum membrane
GO:0005792 microsome
GO:0055114 oxidation-reduction process
GO:0006805 xenobiotic metabolic process
GO:0007140 male meiosis
GO:0007283 spermatogenesis
GO:0008401 retinoic acid 4-hydroxylase activity
GO:0009954 proximal/distal pattern formation
GO:0020037 heme binding
GO:0030326 embryonic limb morphogenesis
GO:0034653 retinoic acid catabolic process
GO:0048387 negative regulation of retinoic acid receptor signaling pathway



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