Cytochrome P450 Aromatase antibody

100% Secure


Rabbit anti Cytochrome P450 Aromatase

Cytochrome P450 aromatase antibody recognizes Cytochrome P450 aromatase, also known as CYP450 family 26 subfamily B member, cytochrome P450 retinoid metabolizing protein or cytochrome P450, family 26, subfamily B, polypeptide 1.

Product Type
PrecisionAb™ Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
VPA00769 WB 100 µl
Rabbit anti Human cytochrome P450 aromatase antibody recognizes cytochrome P450 aromatase, also known as CYP450 family 26 subfamily B member, cytochrome P450 retinoid metabolizing protein or cytochrome P450, family 26, subfamily B, polypeptide 1.

This gene encodes a member of the cytochrome P450 superfamily. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein is localized to the endoplasmic reticulum, and functions as a critical regulator of all-trans retinoic acid levels by the specific inactivation of all-trans retinoic acid to hydroxylated forms. Mutations in this gene are associated with radiohumeral fusions and other skeletal and craniofacial anomalies, and increased levels of the encoded protein are associated with atherosclerotic lesions. Alternative splicing results in multiple transcript variants (provided by RefSeq, Apr 2013).

Rabbit anti Human cytochrome P450 aromatase antibody detects a band of 58 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti cytochrome P450 aromatase antibody recognizes a band of approximately 58 kDa in HepG2 cell lysates
Species Cross-Reactivity
Target SpeciesCross Reactivity
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography on immunogen
Buffer Solution
TRIS buffered glycine
Preservative Stabilisers
0.01% Thiomersal
<20% Glycerol
Immunogen
Recombinant protein encompassing a sequence within the center region of human cytochrome P450 aromatase
Instructions For Use
Please refer to the PrecisionAb western blotting protocol. For additional information on secondary antibody dilution and exposure time see product web page.

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles
Guarantee
As supplied, 12 months from date of despatch

More Information

UniProt
Q9NR63 Related reagents
Entrez Gene
CYP26B1 Related reagents
GO Terms
GO:0009055 electron carrier activity
GO:0001709 cell fate determination
GO:0001972 retinoic acid binding
GO:0005789 endoplasmic reticulum membrane
GO:0005792 microsome
GO:0055114 oxidation-reduction process
GO:0006805 xenobiotic metabolic process
GO:0007140 male meiosis
GO:0007283 spermatogenesis
GO:0008401 retinoic acid 4-hydroxylase activity
GO:0009954 proximal/distal pattern formation
GO:0020037 heme binding
GO:0030326 embryonic limb morphogenesis
GO:0034653 retinoic acid catabolic process
GO:0048387 negative regulation of retinoic acid receptor signaling pathway
Acknowledgements
PrecisionAb™ is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only

Applications of Cytochrome P450 Aromatase antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P 2 ml WB
Op-in to our ecommunications and set your preferences to start receiving resources, protocols, product updates, special offers, and more.

Western Blotting without Trial and Error: Use PrecisionAb™ Antibodies

Watch how PrecisionAb Validated Western Blotting Antibodies are defining a new standard of quality that you can trust to deliver superior results and reproducibility in western blotting.

Contact Information


Online Payment Methods:

  1. Invoice / Purchase Order
  2. Credit Card (Maestro, VISA,MasterCard & VISA Electron)
credit cards accepted