Collagen IV Alpha 5 antibody
Rabbit anti Human collagen IV alpha 5 antibody recognizes collagen IV alpha 5, also known as collagen alpha-5(IV) chain, ATS, COL4A5, ASLN and collagen of basement membrane alpha-5 chain.
COL4A5 encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in COL4A5 are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, COL4A5 is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for COL4A5 (provided by RefSeq, Aug 2010).
Rabbit anti Human collagen IV alpha 5 antibody detects a band of 161 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
COL4A5 encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in COL4A5 are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, COL4A5 is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Alternatively spliced transcript variants have been identified for COL4A5 (provided by RefSeq, Aug 2010).
Rabbit anti Human collagen IV alpha 5 antibody detects a band of 161 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti collagen IV alpha 5 antibody recognizes a band of approximately 161 kDa in RD cell lysates
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography on immunogen
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
<50% Glycerol - Immunogen
- Recombinant protein of human collagen IV alpha 5
Storage Information
- Storage
- Store undiluted at -20°C, avoiding repeated freeze thaw cycles
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P29400
- Entrez Gene
- COL4A5
- GO Terms
- GO:0005515 protein binding
- GO:0005201 extracellular matrix structural constituent
- GO:0005587 collagen type IV
- GO:0007411 axon guidance
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only
Applications of Collagen IV Alpha 5 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
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