Clusterin antibody

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Rabbit anti Clusterin

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Product Code Applications Pack Size List Price Quantity
VPA00671
Datasheet
WB
MSDS
100 µl loader

Rabbit anti Human clusterin antibody recognizes clusterin, also known as apolipoprotein J, complement lysis inhibitor, ku70-binding protein 1, sulfated glycoprotein 2, or testosterone-repressed prostate message 2.

The protein encoded by CLU gene is a secreted chaperone that can under some stress conditions also be found in the cell cytosol. It has been suggested to be involved in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Alternate splicing results in both coding and non-coding variants (provided by RefSeq, May 2011).

Rabbit anti Human clusterin antibody detects a band of 65 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Rabbit anti clusterin detects a band of approximately 65 kDa in A549 cell lysates
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide
2% Sucrose
Immunogen
Synthetic peptide encompassing part of the C terminal region of human clusterin

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Guarantee
12 months from date of despatch

More Information

UniProt
P10909
Entrez Gene
CLU
GO Terms
GO:0001836 release of cytochrome c from mitochondria
GO:0002576 platelet degranulation
GO:0009615 response to virus
GO:0005739 mitochondrion
GO:0006629 lipid metabolic process
GO:0006958 complement activation, classical pathway
GO:0051787 misfolded protein binding
GO:0030168 platelet activation
GO:0031093 platelet alpha granule lumen
GO:0032463 negative regulation of protein homooligomerization
GO:0034366 spherical high-density lipoprotein particle
GO:0043691 reverse cholesterol transport
GO:0045087 innate immune response
GO:0051788 response to misfolded protein
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories
Regulatory
For research purposes only

Applications of Clusterin antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Secondary Antibodies Available

Description Product Code Applications Pack Size List Price Quantity
Goat anti Rabbit IgG (H/L):HRP STAR208P WB 2 ml