CDK5 antibody
Rabbit anti Human CDK5 antibody recognizes cyclin-dependent kinase 5 (CDK5), also known as Tau protein kinase II catalytic subunit, cyclin-dependent-like kinase 5, protein kinase CDK5 splicing or serine/threonine-protein kinase PSSALRE. Mutations in the Cdk5 gene are a cause of lissencephaly 7, with cerebellar hypoplasia (LIS7), a condition characterized by agyria or pachygyria with disruption of cortical lamination (Magen et al. 2015).
Rabbit anti Human CDK5 antibody detects a band of 30 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Rabbit anti Human CDK5 antibody detects a band of 30 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti CDK5 detects a band of approximately 30 kDa in Jurkat cell lysates.
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid.
- Preparation
- Rabbit polyclonal antibody prepared by affinity chromatography on Protein A.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
2% Sucrose. - Immunogen
- Synthetic peptide directed towards the N terminal region of human CDK5
- Approx. Protein Concentrations
- IgG concentration 0.5 mg/ml
Storage Information
- Storage
- Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q00535
- Entrez Gene
- CDK5
- GO Terms
- GO:0016020 membrane
- GO:0007596 blood coagulation
- GO:0005829 cytosol
- GO:0004693 cyclin-dependent protein kinase activity
- GO:0043125 ErbB-3 class receptor binding
- GO:0005176 ErbB-2 class receptor binding
- GO:0005524 ATP binding
- GO:0009790 embryo development
- GO:0008283 cell proliferation
- GO:0030027 lamellipodium
- GO:0030424 axon
- GO:0030425 dendrite
- GO:0030426 growth cone
- GO:0030549 acetylcholine receptor activator activity
- GO:0031594 neuromuscular junction
- GO:0043025 neuronal cell body
- GO:0043525 positive regulation of neuron apoptosis
- GO:0050321 tau-protein kinase activity
- GO:0051301 cell division
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
- Regulatory
- For research purposes only.
Applications of CDK5 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
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