BID antibody
Rabbit anti BID
- Product Type
- PrecisionAb Polyclonal
- Isotype
- Polyclonal IgG
- Format
- Purified
- Specificity
- BID
Antibody Quality and Performance Guarantee
| Rabbit anti Human BID antibody recognizes the BH3-interacting domain death agonist, also known as apoptic death agonist. BID encodes a death agonist that heterodimerizes with either agonist BAX or antagonist Bcl-2. The encoded protein is a member of the Bcl-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined (provided by RefSeq, Jul 2008). Rabbit anti Human BID antibody detects a band of 22 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
|
- Target Species
- Human
- Western Blotting
- Anti BID antibody recognizes a band of approximately 22 kDa in Jurkat cell lysates.
- Product Form
- Purified IgG - liquid
- Preparation
- Rabbit polyclonal antibody purified by affinity chromatography on immunogen.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide
<50% Glycerol - Immunogen
- Recombinant protein of human BID
- Regulatory
- For research purposes only.
- Guarantee
- 12 months from date of despatch.
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Rabbit IgG (H/L):HRP | STAR208P | WB | 2 ml |
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| List Price | Your Price | ||||||
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| Description | Goat anti Rabbit IgG (H/L):HRP | ||||||
- UniProt
- P55957
- Entrez Gene
- BID
- GO Terms
- GO:0001836 release of cytochrome c from mitochondria
- GO:0005829 cytosol
- GO:0005123 death receptor binding
- GO:0005624 membrane fraction
- GO:0005741 mitochondrial outer membrane
- GO:0008625 induction of apoptosis via death domain receptors
- GO:0008629 induction of apoptosis by intracellular signals
- GO:0008633 activation of pro-apoptotic gene products
- GO:0051402 neuron apoptosis
- View More GO Terms
VPA00841
170824
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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