Bap antibody

Rabbit anti Bap

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
Bap

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VPA00614
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Rabbit anti Human BAP antibody recognizes prohibitin-2, also known as B-cell receptor-associated protein BAP37, D-prohibitin, prohibitin-2, REA or repressor of estrogen receptor activity.

Prohibitins are assembled into a ring-like structure with 16–20 alternating Phb1 and Phb2 subunits in the inner mitochondrial membrane.The precise molecular function of the PHB complex is not clear but roles as a chaperone for respiration chain proteins, general structuring scaffold for mitochondrial morphology and function, and transcription factor interactions have all been suggested.

Rabbit anti Human BAP antibody detects a band of 33 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Rabbit anti BAP detects a band of approximately 33 kDa in HEK293 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Rat
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
Phosphate buffered saline.
Preservative Stabilisers
0.09% Sodium Azide
2% Sucrose
Immunogen
Synthetic peptide encompassing part of the C terminal region of human BAP
Approx. Protein Concentrations
IgG concentration 0.5 mg/ml
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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Description Goat anti Rabbit IgG (H/L):HRP

UniProt
Q99623
Entrez Gene
PHB2
GO Terms
GO:0004872 receptor activity
GO:0005634 nucleus
GO:0005743 mitochondrial inner membrane
GO:0006350 transcription
GO:0016566 specific transcriptional repressor activity
GO:0030331 estrogen receptor binding
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

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