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|Rabbit anti Human arginase-1 antibody recognizes arginase-1, also known as liver-type arginase or type I arginase.
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by ARG1 gene is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia (ARGIN), an autosomal recessive disorder characterized by hyperammonemia (Carvalho et al. 2012). Two transcript variants encoding different isoforms have been found for ARG1 (provided by RefSeq, Sep 2011).
Rabbit anti Human arginase-1 antibody detects a band of 38 kDa. The antibody has been extensively validated for western blotting using tissue and whole cell lysates.
- Target Species
- Western Blotting
- Anti arginase-1 detects a band of approximately 38 kDa in human liver tissue lysate.
- Product Form
- Purified IgG - liquid.
- Rabbit polyclonal antibody purified by affinity chromatography.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3).
- KLH conjugated synthetic peptide corresponding to amino acid 293-322 of human arginase-1
- For research purposes only.
- 12 months from date of despatch
- PrecisionAb is a trademark of Bio-Rad Laboratories
|Application Name||Verified||Min Dilution||Max Dilution|
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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