ABL2 antibody

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Anti ABL2 Antibody (PrecisionAb Polyclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with ABL2 antibody followed by detection with HRP conjugated Goat anti Rabbit IgG (1/10,000, STAR208P) and visualized on the ChemiDoc MP with 20 second exposure. Arrow points to ABL2 (molecular weight 128 kDa)

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Rabbit anti ABL2

Product Type: PrecisionAb Polyclonal
Isotype: Polyclonal IgG
Format: Purified
Specificity: ABL2

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VPA00662 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
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Rabbit anti Human ABL2 antibody recognizes ABL proto-oncogene 2 also known as ARG.

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. ABL2 is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. ARG is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene (provided by RefSeq, Nov 2009).

Rabbit anti Human ABL2 antibody detects a band of 128 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Rabbit anti ABL2 detects a band of approximately 128 kDa in HEK293 cell lysates.
Species Cross-Reactivity: Target Species Cross Reactivity

Mouse; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Preparation: Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution: TRIS buffered glycine.
Preservative Stabilisers: 0.01% Thiomersal
<50% Glycerol
Immunogen: Recombinant protein encompassing part of the middle region of human ABL2
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Mouse

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting			1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Rabbit IgG (H/L):HRP	STAR208P	WB	2 ml	Log in	Get Quote
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Description	Goat anti Rabbit IgG (H/L):HRP

UniProt: P42684
Entrez Gene: ABL2
GO Terms: GO:0005515 protein binding; GO:0000287 magnesium ion binding; GO:0007155 cell adhesion; GO:0005829 cytosol; GO:0004715 non-membrane spanning protein tyrosine kinase activity; GO:0007165 signal transduction; GO:0005524 ATP binding; GO:0005856 cytoskeleton; GO:0007411 axon guidance; View More GO Terms; GO:0018108 peptidyl-tyrosine phosphorylation; GO:0030145 manganese ion binding; GO:0051353 positive regulation of oxidoreductase activity