ABL2 antibody

Rabbit anti ABL2

Product Type
PrecisionAb Polyclonal
Isotype
Polyclonal IgG
Format
Purified
Specificity
ABL2

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VPA00662
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Rabbit anti Human ABL2 antibody recognizes ABL proto-oncogene 2 also known as ARG.

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. ABL2 is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. ARG is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene (provided by RefSeq, Nov 2009).

Rabbit anti Human ABL2 antibody detects a band of 128 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
PrecisionAb Antibodies

Target Species
Human
Western Blotting
Rabbit anti ABL2 detects a band of approximately 128 kDa in HEK293 cell lysates.
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Rabbit polyclonal antibody purified by affinity chromatography.
Buffer Solution
TRIS buffered glycine.
Preservative Stabilisers
0.01% Thiomersal
<50% Glycerol
Immunogen
Recombinant protein encompassing part of the middle region of human ABL2
Regulatory
For research purposes only.
Guarantee
12 months from date of despatch.
Acknowledgements
PrecisionAb is a trademark of Bio-Rad Laboratories.

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

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UniProt
P42684
Entrez Gene
ABL2
GO Terms
GO:0005515 protein binding
GO:0000287 magnesium ion binding
GO:0007155 cell adhesion
GO:0005829 cytosol
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0007165 signal transduction
GO:0005524 ATP binding
GO:0005856 cytoskeleton
GO:0007411 axon guidance
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0030145 manganese ion binding
GO:0051353 positive regulation of oxidoreductase activity
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"

View all Anti-Human Products