Coronavirus antibody | FIPV3-70
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Mouse anti Feline Coronavirus
- Product Type
- Monoclonal Antibody
|Mouse anti Feline Coronavirus antibody, clone FIPV3-70 reacts with feline infectious peritonitis virus (FIPV) type 1 and 2 and is specific for the nucleocapsid. It is also known to react with canine coronavirus (CCV), pig coronavirus transmissible gastroenteritis virus (TGEV) and ferret coronavirus. Some specific activity has been detected against bovine coronavirus (BCV).
Mouse anti Feline Coronavirus antibody, clone FIPV3-70 does not recognize Feline Leukemia virus, Feline Immunodeficiency virus, Feline Calcivirus, Feline Herpes virus, Canine Adenovirus (type 2), Canine Distemper virus, Canine Parvovirus and Canine Parainfluenza virus.
It has been reported that clone FIPV3 recognizes the SARS-Cov-2 core protein (Nardacci et al. 2020).
- Target Species
- Product Form
- Purified IgG - liquid
- Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- < 0.1% sodium azide (NaN3)
- Coronavirus cocktail.
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|Immunohistology - Frozen|
|Immunohistology - Paraffin 1|
- 1This product requires antigen retrieval using heat treatment prior to staining of paraffin sections.Sodium citrate buffer pH 6.0 is recommended for this purpose.
- Western Blotting
- Under reducing conditions Mouse anti Feline Coronavirus antibody, clone FIPV3-70 detects a band of 50-56 kDa that represents the nucleocapsid.protein and an additional band 46 kDa in reducing gels with CCV as antigen.
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References for Coronavirus antibody
Kipar, A. et al. (1998) Fatal enteritis associated with coronavirus infection in cats.
J Comp Pathol. 119 (1): 1-14.
Kipar, A. et al. (2000) Expression of viral proteins in feline leukemia virus-associated enteritis.
Vet Pathol. 37 (2): 129-36.
Michimae, Y. et al. (2010) The First Case of Feline Infectious Peritonitis-like Pyogranuloma in a Ferret Infected by Coronavirus in Japan.
J Toxicol Pathol. 23 (2): 99-101.
Suderman, M.T. et al. (2006) Three-Dimensional Human Bronchial-Tracheal Epithelial Tissue-Like Assemblies (TLAs) as Hosts For Severe Acute Respiratory Syndrome (SARS)-CoV Infection
Vogel, L. et al. (2010) Pathogenic characteristics of persistent feline enteric coronavirus infection in cats.
Vet Res. 41 (5): 71.
Cony, F.G. et al. (2019) Clinical and pathological aspects of idiopathic pulmonary fibrosis in cats
Pesquisa Veterinária Brasileira. 39 (2): 134-41.
Stranieri, A. et al. (2020) Concordance between Histology, Immunohistochemistry, and RT-PCR in the Diagnosis of Feline Infectious Peritonitis
Pathogens. 9 (10): 852.
Stranieri, A. et al. (2020) Preliminary investigation on feline coronavirus presence in the reproductive tract of the tom cat as a potential route of viral transmission.
J Feline Med Surg. 22 (2): 178-85.
View The Latest Product References
Meazzi, S. et al. (2019) Feline gut microbiota composition in association with feline coronavirus infection: A pilot study.
Res Vet Sci. 125: 272-8.
MCA2194154272 155364 158174
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"View all Anti-Viral Products
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