Kinetoplastid Membrane Protein 11 antibody | L-157
Mouse anti Kinetoplastid Membrane Protein 11
- Product Type
- Monoclonal Antibody
- Kinetoplastid Membrane Protein 11
|Mouse anti Kinetoplastid Membrane Protein 11 antibody, clone L-157 recognizes Kinetoplastid Membrane Protein-11 (KMP-11), previously known as the lipophosphoglycan-associated protein (LPGAP), a 92 amino acid ~11 kDa membrane protein. Mouse anti Kinetoplastid Membrane Protein 11 antibody, clone L-157 was originally derived against Leishmania donovani lipophosphoglycan, but found to recognize the tightly associated LPGAP. KMP-11 is found in a wide variety of Kinetoplastid parasites including African trypanosomes, Leishmania and Crithidia (Tolson et al. 1994).|
- Target Species
- Product Form
- Ascites - lyophilized
- Reconstitute with 0.5 ml distilled water
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
- Preservative Stabilisers
- None present
- L. donovani lipophosphoglycan semi purified from epimastigotes.
- Fusion Partners
- Spleen cells from immunized BALB/c mice were fused with cells of the SP2/0 myeloma cell line.
- For research purposes only
- 12 months from date of despatch
After reconstitution store at -20oC.
Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
|Application Name||Verified||Min Dilution||Max Dilution|
Tolson, D.L. et al. (1989) The immunochemical structure and surface arrangement of Leishmania donovani lipophosphoglycan determined using monoclonal antibodies.
Mol Biochem Parasitol. 35 (2): 109-18.
References for Kinetoplastid Membrane Protein 11 antibody
McNeely, T.B. et al. (1990) Characterization of Leishmania donovani variant clones using anti-lipophosphoglycan monoclonal antibodies.
Glycobiology. 1 (1): 63-9.
Jardim, A. et al. (1991) The Leishmania donovani lipophosphoglycan T lymphocyte-reactive component is a tightly associated protein complex.
J Immunol. 147 (10): 3538-44.
Tolson, D.L. et al. (1994) The kinetoplastid membrane protein 11 of Leishmania donovani and African trypanosomes is a potent stimulator of T-lymphocyte proliferation.
Infect Immun. 62 (11): 4893-9.
Pearson, T.W. et al. (2000) The major cell surface glycoprotein procyclin is a receptor for induction of a novel form of cell death in African trypanosomes in vitro.
Mol Biochem Parasitol. 111 (2): 333-49.
Jardim, A. et al. (2002) Peroxisomal targeting protein 14 (PEX14) from Leishmania donovani. Molecular, biochemical, and immunocytochemical characterization.
Mol Biochem Parasitol. 124 (1-2): 51-62.
Always be the first to know.
When we launch new products and resources to help you achieve more in the lab.Yes, sign me up