CD90 antibody | F7D5
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|Mouse anti Mouse CD90 antibody, clone F7D5 recognizes the mouse Thy1.2 alloantigen, also known as CD90.2, which is expressed by thymocytes and peripheral T lymphocytes. Clone F7D5 reacts with Thy1.2 mice such as CBA and BALB/C, but not with Thy1.1 mice eg. AKR and FUB.
The antibody is particularly useful for removal of T lymphocytes from cell populations by complement mediated cytotoxicity (Lake et al. 1979).
Mouse anti Mouse CD90 antibody, clone F7D5 is routinely tested in flow cytometry using mouse thymocytes.
- Target Species
- Product Form
- IgM fraction - liquid.
- IgM fraction prepared by ammonium sulphate precipitation from tissue culture supernatant.
- Buffer Solution
- Phosphate buffered saline.
- Preservative Stabilisers
0.09% sodium azide.
- Approx. Protein Concentrations
- IgM concentration 1.0 mg/ml.
- Fusion Partners
- Spleen cells from immunised AKR mice were fused with cells of the mouse NS-1 myeloma cell line.
- For research purposes only.
- 12 months from date of despatch.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
|Description||Product Code||Applications||Pack Size||List Price||Your Price||Quantity|
|Goat anti Mouse IgG/A/M:Alk. Phos.||STAR87A||C E WB||1 mg||Log in|
|List Price||Your Price|
|Description||Goat anti Mouse IgG/A/M:Alk. Phos.|
|Goat anti Mouse IgG/A/M:HRP (Human Adsorbed)||STAR87P||E||1 mg||Log in|
|List Price||Your Price|
|Description||Goat anti Mouse IgG/A/M:HRP (Human Adsorbed)|
|Goat anti Mouse IgM:Alk. Phos.(Human Adsorbed)||STAR138A||C E P WB||1 ml||Log in|
|List Price||Your Price|
|Description||Goat anti Mouse IgM:Alk. Phos.(Human Adsorbed)|
|Human anti Mouse IgM:FITC||HCA040F||F||0.1 mg||Log in|
|List Price||Your Price|
|Description||Human anti Mouse IgM:FITC|
References for CD90 antibody
Lake, P. et al. (1979) Production and characterization of cytotoxic Thy-1 antibody-secreting hybrid cell lines. Detection of T cell subsets.
Eur J Immunol. 9 (11): 875-86.
Yoshida, K. et al. (2002) Evidence for shared recognition of a peptide ligand by a diverse panel of non-obese diabetic mice-derived, islet-specific, diabetogenic T cell clones.
Int Immunol. 14 (12): 1439-47.
DeVries-vanDerZwan, A. et al. (1997) Specific tolerance induction and transplantation: a single-day protocol.
Blood. 89 (7): 2596-601.
Winzeler, A.M. et al. (2011) The lipid sulfatide is a novel myelin-associated inhibitor of CNS axon outgrowth.
J Neurosci. 31: 6481-92.
Unterlauft, J.D. et al. (2014) Enhanced survival of retinal ganglion cells is mediated by Müller glial cell-derived PEDF.
Exp Eye Res. 127: 206-14.
Brown, R.L. et al. (2015) TRPM3 Expression in Mouse Retina.
PLoS One. 10: e0117615.
Hanafusa, T. et al. (1988) Induction of insulitis by adoptive transfer with L3T4+Lyt2- T-lymphocytes in T-lymphocyte-depleted NOD mice.
Diabetes. 37: 204-8.
Billiau, A.D. et al. (2003) Transient expansion of Mac1+Ly6-G+Ly6-C+ early myeloid cells with suppressor activity in spleens of murine radiation marrow chimeras: possible implications for the graft-versus-host and graft-versus-leukemia reactivity of donor lymphocyte infusions.
Blood. 102: 740-8.
View The Latest Product References
Raeber, A.J. et al. (1999) PrP-dependent association of prions with splenic but not circulating lymphocytes of scrapie-infected mice.
EMBO J. 18: 2702-6.
Wang, X. et al. (2001) Functional soluble CD100/Sema4D released from activated lymphocytes: possible role in normal and pathologic immune responses.
Blood. 97 (11): 3498-504.
Billiau, A.D. et al. (2002) Crucial role of timing of donor lymphocyte infusion in generating dissociated graft-versus-host and graft-versus-leukemia responses in mice receiving allogeneic bone marrow transplants.
Blood. 100 (5): 1894-902.
Ishikawa, N. et al. (1998) Early cytokine responses during intestinal parasitic infections.
Immunology. 93 (2): 257-63.
Ishigaki, H. et al. (2006) Preparation and functional analysis of tumor-infiltrating stroma cells using bone marrow chimera mice.
Microbiol Immunol. 50 (8): 655-62.
Logan, G.J. et al. (2004) CD4 expression on EL4 cells as an epiphenomenon of retroviral transduction and selection.
Immunol Cell Biol. 82 (2): 132-5.
Gobin, V. et al. (2013) Fluoxetine reduces murine graft-versus-host disease by induction of T cell immunosuppression.
J Neuroimmune Pharmacol. 8 (4): 934-43.
van Pel, M. et al. (2003) Towards a myeloablative regimen with clinical potential: I. Treosulfan conditioning and bone marrow transplantation allow induction of donor-specific tolerance for skin grafts across full MHC barriers.
Bone Marrow Transplant. 32 (1): 15-22.
Oosterwegel, M.A. et al. (1999) The role of CTLA-4 in regulating Th2 differentiation.
J Immunol. 163 (5): 2634-9.
Vadivelu, S. et al. (2015) NG2+ Progenitors Derived From Embryonic Stem Cells Penetrate Glial Scar and Promote Axonal Outgrowth Into White Matter After Spinal Cord Injury.
Stem Cells Transl Med. pii: sctm.2014-0107.
Wang, Y.L. et al. (2015) Electrospun and woven silk fibroin/poly(lactic-co-glycolic acid) nerve guidance conduits for repairing peripheral nerve injury.
Neural Regen Res. 10 (10): 1635-42.
Liu, X. et al. (2017) Thy-1 interaction with Fas in lipid rafts regulates fibroblast apoptosis and lung injury resolution.
Lab Invest. (3): 256-67.
Naaldijk, Y. et al. (2016) Effect of systemic transplantation of bone marrow-derived mesenchymal stem cells on neuropathology markers in APP/PS1 Alzheimer mice.
Neuropathol Appl Neurobiol. Feb 26. [Epub ahead of print]
Bernard-Marissal, N. et al. (2015) Dysfunction in endoplasmic reticulum-mitochondria crosstalk underlies SIGMAR1 loss of function mediated motor neuron degeneration.
Brain. 138 (Pt 4): 875-90.
Takahama, S. et al. (2017) Retinal Astrocytes and GABAergic Wide-Field Amacrine Cells Express PDGFRα: Connection to Retinal Ganglion Cell Neuroprotection by PDGF-AA.
Invest Ophthalmol Vis Sci. 58 (11): 4703-11.
Zhu, B. et al. (2019) GAIN domain-mediated cleavage is required for activation of G protein-coupled receptor 56 (GPR56) by its natural ligands and a small-molecule agonist.
J Biol Chem. pii: jbc.RA119.008234. Oct 18 [Epub ahead of print].
Bürger, S. et al. (2020) Pigment Epithelium-Derived Factor (PEDF) Receptors Are Involved in Survival of Retinal Neurons.
Int J Mol Sci. 22 (1): 369.
Qiu, A.W. et al. (2021) IL-17A injury to retinal ganglion cells is mediated by retinal Müller cells in diabetic retinopathy.
Cell Death Dis. 12 (11): 1057.
Xing, J. et al. (2021) Post-injury born oligodendrocytes integrate into the glial scar and inhibit growth of regenerating axons by premature myelination
boRxiv. Oct 20 [Epub ahead of print].
- Entrez Gene
- GO Terms
- GO:0001525 angiogenesis
- GO:0007010 cytoskeleton organization
- GO:0005100 Rho GTPase activator activity
- GO:0006469 negative regulation of protein kinase activity
- GO:0016337 cell-cell adhesion
- GO:0030336 negative regulation of cell migration
- GO:0030425 dendrite
- GO:0030426 growth cone
- GO:0031362 anchored to external side of plasma membrane
- View More GO Terms
- GO:0034235 GPI anchor binding
- GO:0043547 positive regulation of GTPase activity
- GO:0045121 membrane raft
- GO:0046549 retinal cone cell development
- GO:0048041 focal adhesion assembly
- GO:0050771 negative regulation of axonogenesis
- GO:0050852 T cell receptor signaling pathway
- GO:0050860 negative regulation of T cell receptor signaling pathway
- GO:0050870 positive regulation of T cell activation
- GO:0051281 positive regulation of release of sequestered calcium ion into cytosol
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