RUVBL1 antibody | AB04/2E9
Mouse anti Human RUVBL1 antibody recognizes RuvB-like 1 protein, also known as 49 kDa TATA box-binding protein-interacting protein, ECP-54, INO80 complex subunit H, NMP 238 or pontin 52.
The RUVBL1 gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants (provided by RefSeq, Jan 2016)
Mouse anti Human RuvB-like 1 antibody detects a band of 50 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
The RUVBL1 gene encodes a protein that has both DNA-dependent ATPase and DNA helicase activities and belongs to the ATPases associated with diverse cellular activities (AAA+) protein family. The encoded protein associates with several multisubunit transcriptional complexes and with protein complexes involved in both ATP-dependent remodeling and histone modification. Alternate splicing results in multiple transcript variants (provided by RefSeq, Jan 2016)
Mouse anti Human RuvB-like 1 antibody detects a band of 50 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti RUVBL1 detects a band of approximately 50 kDa in K562 cell lysates
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- E. coli-derived recombinant human RUVBL1 (amino acids 1 - 456)
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- 12 months from date of despatch
More Information
- UniProt
- Q9Y265
- Entrez Gene
- RUVBL1
- GO Terms
- GO:0005515 protein binding
- GO:0003678 DNA helicase activity
- GO:0016020 membrane
- GO:0005524 ATP binding
- GO:0005794 Golgi apparatus
- GO:0005815 microtubule organizing center
- GO:0006310 DNA recombination
- GO:0006350 transcription
- GO:0006357 regulation of transcription from RNA polymerase II promoter
- GO:0007067 mitosis
- GO:0007283 spermatogenesis
- GO:0016363 nuclear matrix
- GO:0034080 CenH3-containing nucleosome assembly at centromere
- GO:0035267 NuA4 histone acetyltransferase complex
- GO:0040008 regulation of growth
- GO:0043967 histone H4 acetylation
- GO:0043968 histone H2A acetylation
- GO:0051301 cell division
- GO:0071339 MLL1 complex
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of RUVBL1 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
