RPS6KA3 antibody

ISO 9001 Quality Assurance Manufacturing | Print

Anti RPS6KA3 Antibody (PrecisionAb Monoclonal Antibody) gallery image 1 — Western blot analysis of whole cell lysates probed with RPS6KA3 antibody followed by detection with HRP conjugated Goat anti Mouse IgG antibody (1/10,000, STAR207P) and visualized on the ChemiDoc MP with 72 second exposure. Arrow points to RPS6KA3 (molecular weight 83 kDa).

Filter by Application:

Mouse anti RPS6KA3

Product Type: PrecisionAb Monoclonal
Isotype: IgG1
Format: Purified
Specificity: RPS6KA3

Quick Links:

Secondary Antibodies
Applications
Storage Information
Batch/Lot Specific Datasheets

Antibody Quality and Performance Guarantee

Unrivaled Technical Support

Product Code Applications Pack Size List Price Your Price Qty

List Price	Your Price
VMA00459 Datasheet Datasheet SDS SDS	WB	100 µl		Log in	Get Quote
	Log in

Mouse anti Human RPS6KA3 antibody recognizes the ribosomal protein S6 kinase alpha-3, also known as MAP kinase-activated protein kinase 1b, insulin-stimulated protein kinase 1, p90-RSK 3 or ribosomal S6 kinase 2.

RPS6KA3 encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in RPS6KA3 gene have been associated with Coffin-Lowry syndrome (CLS) (provided by RefSeq, Jul 2008), additionally mutations in the RPS6KA3 gene have been associated with a non-syndromic mental retardation X-linked-19 (MRX19).

Mouse anti Human RPS6KA3 antibody detects a band of 83 kDa. The antibody has been extensively validated for western blotting using whole cell lysates.

Target Species: Human
Western Blotting: Anti RPS6KA3 detects a band of approximately 83 kDa in A431 cell lysate.
Species Cross-Reactivity: Target Species Cross Reactivity

Rat; N.B. Antibody reactivity and working conditions may vary between species.
Product Form: Purified IgG - liquid
Preparation: Mouse monoclonal antibody isolated from ascites by saturated ammonium sulfate precipitation followed by dialysis against PBS.
Buffer Solution: Phosphate buffered saline.
Preservative Stabilisers: 0.09% Sodium Azide (NaN₃).
Immunogen: Purified His-tagged fragment of human RPS6KA3
Regulatory: For research purposes only.
Guarantee: 12 months from date of despatch.
Acknowledgements: PrecisionAb is a trademark of Bio-Rad Laboratories.

Target Species	Cross Reactivity
Rat

Store undiluted at -20°C, avoiding repeated freeze thaw cycles.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
Western Blotting		1/1000

The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.

Description	Product Code	Applications	Pack Size	Your Price
Goat anti Mouse IgG (H/L):HRP	STAR207P	WB	2 ml	Log in	Get Quote
List Price	Your Price
	Log in
Description	Goat anti Mouse IgG (H/L):HRP

UniProt: P51812
Entrez Gene: RPS6KA3
GO Terms: GO:0000287 magnesium ion binding; GO:0001501 skeletal system development; GO:0002755 MyD88-dependent toll-like receptor signaling pathway; GO:0002756 MyD88-independent toll-like receptor signaling pathway; GO:0005829 cytosol; GO:0004674 protein serine/threonine kinase activity; GO:0005524 ATP binding; GO:0005654 nucleoplasm; GO:0006468 protein phosphorylation; View More GO Terms; GO:0007268 synaptic transmission; GO:0007411 axon guidance; GO:0007417 central nervous system development; GO:0008063 Toll signaling pathway; GO:0034130 toll-like receptor 1 signaling pathway; GO:0034134 toll-like receptor 2 signaling pathway; GO:0034138 toll-like receptor 3 signaling pathway; GO:0034142 toll-like receptor 4 signaling pathway; GO:0045087 innate immune response; GO:0048011 nerve growth factor receptor signaling pathway; GO:0051403 stress-activated MAPK cascade