RPS5 antibody | rCD02-2C12
Mouse anti RPS5
- Product Type
- PrecisionAb Monoclonal
- Clone
- rCD02-2C12
- Isotype
- IgG2b
- Format
- Purified
- Specificity
- RPS5
Mouse anti RPS5 antibody recognizes 40S ribosomal protein S5 (RPS5). Ribosomes are complexes that translate mRNA into protein, and consist of a small 40S subunit and a large 60S subunit (Ameismeier et al. 2018). RPS5 is a component of the 40S subunit of ribosomes (Visweswaraiah and Hinnebusch 2017). RPS5 has been found to regulate P13K/Akt, NF-kappaB and MAP kinase (MAPK) pathways in osteoclastogenesis, and has been suggested as a potential target for treatment of osteoporosis (Chen et al. 2017). Many mammalian ribosomal proteins, including RPS5, appear to also have non-mitochondrial roles. RPS5 has been found to enter the nucleus and nucleoli in mouse cells (Matragkou et al. 2009). |
- Target Species
- Human
- Western Blotting
- Mouse anti RPS5 antibody detects a band of approximately 23 kDa in Jurkat cell lysates
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Recombinant IgG prepared by affinity chromatography on Protein A from cell culture supernatant
- Source
- CHO-S
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- E. coli--derived recombinant protein of amino acids 1-204 of human RPS5
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- As supplied, 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
Application Name | Verified | Min Dilution | Max Dilution |
---|---|---|---|
Western Blotting | 1/2000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
- UniProt
- P46782
- Entrez Gene
- RPS5
- GO Terms
- GO:0022627 cytosolic small ribosomal subunit
- GO:0003729 mRNA binding
- GO:0003735 structural constituent of ribosome
- GO:0006413 translational initiation
- GO:0006414 translational elongation
- GO:0006415 translational termination
- GO:0006450 regulation of translational fidelity
- GO:0019083 viral transcription
- GO:0031018 endocrine pancreas development
- View More GO Terms
VMA00903
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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