RPS5 antibody | rCD02-2C12
Mouse anti RPS5
- Product Type
- PrecisionAb Monoclonal
- Clone
- rCD02-2C12
- Isotype
- IgG2b
- Format
- Purified
- Specificity
- RPS5
Antibody Quality and Performance Guarantee
| Mouse anti RPS5 antibody recognizes 40S ribosomal protein S5 (RPS5). Ribosomes are complexes that translate mRNA into protein, and consist of a small 40S subunit and a large 60S subunit (Ameismeier et al. 2018). RPS5 is a component of the 40S subunit of ribosomes (Visweswaraiah and Hinnebusch 2017). RPS5 has been found to regulate P13K/Akt, NF-kappaB and MAP kinase (MAPK) pathways in osteoclastogenesis, and has been suggested as a potential target for treatment of osteoporosis (Chen et al. 2017). Many mammalian ribosomal proteins, including RPS5, appear to also have non-mitochondrial roles. RPS5 has been found to enter the nucleus and nucleoli in mouse cells (Matragkou et al. 2009). |
|
- Target Species
- Human
- Western Blotting
- Mouse anti RPS5 antibody detects a band of approximately 23 kDa in Jurkat cell lysates
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Recombinant IgG prepared by affinity chromatography on Protein A from cell culture supernatant
- Source
- CHO-S
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- E. coli--derived recombinant protein of amino acids 1-204 of human RPS5
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Regulatory
- For research purposes only
- Guarantee
- As supplied, 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories
Store undiluted at -20oC, avoiding repeated freeze thaw cycles
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/2000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
- UniProt
- P46782
- Entrez Gene
- RPS5
- GO Terms
- GO:0022627 cytosolic small ribosomal subunit
- GO:0003729 mRNA binding
- GO:0003735 structural constituent of ribosome
- GO:0006413 translational initiation
- GO:0006414 translational elongation
- GO:0006415 translational termination
- GO:0006450 regulation of translational fidelity
- GO:0019083 viral transcription
- GO:0031018 endocrine pancreas development
- View More GO Terms
VMA00903
100005042
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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