PSD95 antibody
Mouse anti Human PSD95 antibody recognizes PSD95, also known as DLG4, tax interaction protein 15, postsynaptic density protein 95 or synapse-associated protein 90.
The DLG4 gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for DLG4 (provided by RefSeq, Jul 2008).
Mouse anti Human PSD95 antibody detects a band of 95 kDa. The antibody has been extensively validated for western blotting using tissue and whole cell lysates.
The DLG4 gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for DLG4 (provided by RefSeq, Jul 2008).
Mouse anti Human PSD95 antibody detects a band of 95 kDa. The antibody has been extensively validated for western blotting using tissue and whole cell lysates.
Product Details
- Target Species
- Human
- Western Blotting
- Anti PSD95 detects a band of approximately 95 kDa in mouse brain tissue lysate
- Species Cross-Reactivity
-
Target Species Cross Reactivity Mouse - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - liquid
- Preparation
- Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
- Immunogen
- Fusion protein corresponding to amino acids 77-200 of human PSD95
Storage Information
- Storage
- Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
- Guarantee
- As supplied, 12 months from date of despatch.
More Information
- UniProt
- P78352 Related reagents
- Entrez Gene
- DLG4 Related reagents
- GO Terms
- GO:0005515 protein binding
- GO:0007165 signal transduction
- GO:0006461 protein complex assembly
- GO:0007268 synaptic transmission
- GO:0007411 axon guidance
- GO:0007612 learning
- GO:0008022 protein C-terminus binding
- GO:0014069 postsynaptic density
- GO:0019717 synaptosome
- GO:0030054 cell junction
- GO:0030666 endocytic vesicle membrane
- GO:0030863 cortical cytoskeleton
- GO:0045211 postsynaptic membrane
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
- Regulatory
- For research purposes only
Applications of PSD95 antibody
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting | 1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
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Secondary Antibodies Available
| Description | Product Code | Applications | Pack Size | List Price | Quantity |
|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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