PSD95 antibody

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Mouse anti PSD95

Mouse anti-human PSD95 antibody recognizes disks large homolog 4, also known as Tax interaction protein 15, post-synaptic density protein 95 or synapse-associated protein 90. This antibody has been extensively validated for western blotting using whole cell lysates.

Product Type
PrecisionAb™ Monoclonal
Isotype
IgG2a
Format
Purified
Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
VMA00479 WB 100 µl
Mouse anti Human PSD95 antibody recognizes PSD95, also known as DLG4, tax interaction protein 15, postsynaptic density protein 95 or synapse-associated protein 90.

The DLG4 gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with another MAGUK protein, DLG2, and is recruited into NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins. Multiple transcript variants encoding different isoforms have been found for DLG4 (provided by RefSeq, Jul 2008).

Mouse anti Human PSD95 antibody detects a band of 95 kDa. The antibody has been extensively validated for western blotting using tissue and whole cell lysates.

Product Details

Target Species
Human
Western Blotting
Anti PSD95 detects a band of approximately 95 kDa in mouse brain tissue lysate
Species Cross-Reactivity
Target SpeciesCross Reactivity
Mouse
N.B. Antibody reactivity and working conditions may vary between species.
Product Form
Purified IgG - liquid
Preparation
Mouse monoclonal antibody purified by affinity chromatography on Protein G from tissue culture supernatant
Buffer Solution
Phosphate buffered saline
Preservative Stabilisers
0.09% Sodium Azide (NaN3)
Immunogen
Fusion protein corresponding to amino acids 77-200 of human PSD95
Instructions For Use
Please refer to the PrecisionAb western blotting protocol. For additional information on secondary antibody dilution and exposure time see product web page.

Storage Information

Storage
Store undiluted at -20oC, avoiding repeated freeze thaw cycles.
Shelf Life
As supplied, 12 months from date of despatch.

More Information

UniProt
P78352 Related reagents
Entrez Gene
DLG4 Related reagents
GO Terms
GO:0005515 protein binding
GO:0007165 signal transduction
GO:0006461 protein complex assembly
GO:0007268 synaptic transmission
GO:0007411 axon guidance
GO:0007612 learning
GO:0008022 protein C-terminus binding
GO:0014069 postsynaptic density
GO:0019717 synaptosome
GO:0030054 cell junction
GO:0030666 endocytic vesicle membrane
GO:0030863 cortical cytoskeleton
GO:0045211 postsynaptic membrane
Acknowledgements
PrecisionAbâ„¢ is a trademark of Bio-Rad Laboratories.
Regulatory
For research purposes only

Applications of PSD95 antibody

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
Application Name Verified Min Dilution Max Dilution
Western Blotting 1/1000

PrecisionAb antibodies have been extensively validated for the western blot application. The antibody has been validated at the suggested dilution. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependant on sample type.

Secondary Antibodies Available

Description Product Code Pack Size Applications List Price Quantity
Goat anti Mouse IgG (H/L):HRP STAR207P 2 ml WB

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