PP1 Alpha antibody | OTI6E5
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WB ResetMouse anti PP1 Alpha
- Product Type
- PrecisionAb Monoclonal
- Clone
- OTI6E5
- Isotype
- IgG1
- Format
- Purified
- Specificity
- PP1 Alpha
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| Mouse anti Human PP1 alpha antibody recognizes PP1 alpha, also known as protein phosphatase 1-alpha isoform and serine/threonine protein phosphatase PP1-alpha 1 catalytic subunit. The protein encoded by PPP1CA is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure and is an important regulator of cardiac function. PP1 also appears to function as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for PPP1CA (provided by RefSeq, Jul 2008). Mouse anti Human PP1 alpha antibody detects a band of 38 kDa. The antibody has been extensively validated for western blotting using whole cell lysates. |
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- Target Species
- Human
- Western Blotting
- Mouse anti PP1 alpha detects a band of approximately 38 kDa in Jurkat cell lysates
- Species Cross-Reactivity
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Target Species Cross Reactivity Mouse Rat - N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified IgG - Liquid
- Preparation
- Mouse monoclonal antibody affinity purified on Protein G from ascites
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide
1% Bovine Serum Albumin - Immunogen
- E. coli-derived full length recombinant protein of human PP1 alpha
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
- Acknowledgements
- PrecisionAb is a trademark of Bio-Rad Laboratories.
Store undiluted at -20°C, avoiding repeated freeze thaw cycles
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Western Blotting |  |
1/1000 |
The PrecisionAb label is reserved for antibodies that meet the defined performance criteria within Bio-Rad's ongoing antibody validation programme. Click here to learn how we validate our PrecisionAb range. Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Further optimization may be required dependent on sample type.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Goat anti Mouse IgG (H/L):HRP | STAR207P | WB | 2 ml |
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| List Price | Your Price | ||||||
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| Description | Goat anti Mouse IgG (H/L):HRP | ||||||
- UniProt
- P62136
- Entrez Gene
- PPP1CA
- GO Terms
- GO:0005515 protein binding
- GO:0005829 cytosol
- GO:0004722 protein serine/threonine phosphatase activity
- GO:0046872 metal ion binding
- GO:0005730 nucleolus
- GO:0005977 glycogen metabolic process
- GO:0006470 protein dephosphorylation
- GO:0007049 cell cycle
- GO:0008599 protein phosphatase type 1 regulator activity
- View More GO Terms
- GO:0019433 triglyceride catabolic process
- GO:0051301 cell division
- GO:0070688 MLL5-L complex
- GO:0072357 PTW/PP1 phosphatase complex
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Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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