CD52 antibody | Campath-1H
Human anti CD52 (Alemtuzumab Biosimilar)
Anti-CD52 Antibody is a non-therapeutic biosimilar of the monoclonal antibody drug alemtuzumab (Lemtrada) for research use. It can be used in bioanalytical assays and for studying biological pathways affected by the drug.
- Product Type
- Monoclonal Antibody
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Human Anti-CD52 Antibody is for research use only. It is suitable as a reference standard in a pharmacokinetic (PK) bridging ELISA with anti-alemtuzumab antibodies, for example HCA198 and HCA175. It can also be used as capture and detection reagent in an anti-drug antibody (ADA) bridging ELISA, with an anti-alemtuzumab antibody in IgG1 format as reference standard, for example HCA175.
Alemtuzumab is a drug used in the treatment of chronic lymphocytic leukemia (CLL), cutaneous T-cell lymphoma (CTCL) and T-cell lymphoma. Alemtuzumab is also used in some conditioning regimes for bone marrow transplantation, kidney transplantation and islet cell transplantation along with clinical trial protocols for treatment of certain autoimmune diseases including multiple sclerosis.
This product is NOT FOR THERAPEUTIC USE.
View a summary of supporting anti-alemtuzumab antibody products
- Target Species
- Product Form
- Human IgG1 (kappa) antibody - liquid
- Purified IgG prepared by affinity chromatography on Protein A
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.02% Proclin 300
- Human lymphocytes
- >98% by SDS PAGE
- Approx. Protein Concentrations
- IgG concentration 1.0 mg/ml
- Store at +4oC or at -20oC if preferred.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
- Shelf Life
- 12 months from date of despatch
- P31358 Related reagents
- Entrez Gene
- CD52 Related reagents
- GO Terms
- GO:0005887 integral to plasma membrane
- GO:0005624 membrane fraction
- GO:0007204 elevation of cytosolic calcium ion concentration
- GO:0031225 anchored to membrane
- GO:0045730 respiratory burst
- Licensed Use
- For in vitro research purposes only. Research grade biosimilar. Not for use in therapeutic or diagnostic procedures for humans or animals.
- For research purposes only
Applications of CD52 antibody
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