CCL17 antibody | I11-2A1
Mouse anti Human CCL17:Biotin
- Product Type
- Monoclonal Antibody
- Clone
- I11-2A1
- Isotype
- IgG1
- Specificity
- CCL17
Antibody Quality and Performance Guarantee
| Mouse anti Human CCL17 antibody, clone I11-2A1recognizes C-C motif chemokine 17, also known as TARC and SCYA17. CCL17 is a C-C chemokine highly expressed by the thymus and other cell types, including fibroblasts (Li et al. 2019). CCL17 induces and enhances a broad spectrum of immune reactions, including some contact hypersensitivity reactions, allograft rejections, inflammatory bowel disease, atopic dermatitis and atherosclerosis (Scheu et al. 2017). Therapeutic use of antibodies to neutralize CCL17 can block influx of T cells and ameliorate the impact of various diseases (Teplyakov et al. 2017). Upregulation of CCL17 has been reported in breast cancer, and predicts a decrease in overall survival for patients with breast cancer (Li et al. 2019). The biotinylated Mouse anti Human CCL17 antibody, clone I11-2A1 (MCA6181B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human CCL17 antibody, clone I02-2A4 (MCA6180GA) as the capture antibody. |
- Target Species
- Human
- Product Form
- Purified IgG conjugated to Biotin - liquid
- Preparation
- Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- 0.09% Sodium Azide (NaN3)
1% Bovine Serum Albumin - Immunogen
- E. coli derived recombinant human full length CCL17 (Ala24-Ser94)
- Approx. Protein Concentrations
- IgG concentration 0.1 mg/ml
- Fusion Partners
- Cell fusion between immunized BALB/c mouse spleen cells and mouse myeloma SP2/0
- Regulatory
- For research purposes only
- Guarantee
- 12 months from date of despatch
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunoassay |  |
1.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
| Description | Product Code | Applications | Pack Size | List Price | Your Price | Quantity | |
|---|---|---|---|---|---|---|---|
| Mouse anti Human CCL17 | MCA6180GA | IY | 0.1 mg |
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| Description | Mouse anti Human CCL17 | ||||||
| Recombinant Human CCL17 | PHP295 | E | 10 µg | Log in | |||
| List Price | Your Price | ||||||
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| Description | Recombinant Human CCL17 | ||||||
- Synonyms
- TARC
- UniProt
- Q92583
- Entrez Gene
- CCL17
- GO Terms
- GO:0005615 extracellular space
- GO:0006935 chemotaxis
- GO:0006954 inflammatory response
- GO:0006955 immune response
- GO:0007186 G-protein coupled receptor protein signaling pathway
- GO:0007267 cell-cell signaling
- GO:0007275 multicellular organismal development
- GO:0008009 chemokine activity
MCA6181B
100005229
If you cannot find the batch/lot you are looking for please contact our technical support team for assistance.
View more products with CCL17 specificity
Please Note: All Products are "FOR RESEARCH PURPOSES ONLY"
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