MMP-7 Antibody

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  • Goat anti Human MMP-7
(Rated 0.0 out of 5 based on 0 customer reviews)
  • Product Type
    Polyclonal Antibody
  • Isotype
    Polyclonal IgG
1 Formats Available
    Product CodeApplicationsDatasheetMSDSPack SizeList PriceQuantity
    AHP1081E, WBdatasheet pdfdatasheet pdf0.1 mg
    AHP1081
    Summary
    Secondary Antibodies
    Negative Isotype Controls
    Useful Reagents
    Positive Controls
    Histology Controls
    More Images
    References
    Reviews
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    • Goat anti Huma MMP7 antibody recognises matrix metalloproteinase 7 (MMP7), a ~30 kDa member of the MMP family. MMP's are secreted as inactive zymogens which are activated when proteolytically cleaved by extracellular proteinases. They are involved in processes such as embryonic development, reproduction and tissue remodelling where they breakdown the extracellular matrix. This action is also exploited by diseases processes including arthritis and metastasis. MMP7 degrades casein, fibronectin, gelatin types I, III, IV, V, and activates procollagenase. This metalloproteinase has been identified as an activator of the Notch signalling pathway, and is also involved in wound healing and the regulation of defensins in intestinal mucosa.
    • Intended Use
    • Target Species
      Human
    • Product Form
      Purified IgG - liquid
    • Reconstitution
    • Preparation
    • Antiserum Preparation
      Antisera to human MMP7 were raised by repeated immunisations of goats with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
    • Preservative Stabilisers
      0.02%Sodium Azide
      0.5%Bovine Serum Albumin
    • Immunogen
      Peptide sequence C-QKLYGKRSNSRKK corresponding to the C-terminus of MMP7 (NP_002414.1).
    • Purity
    • Approx. Protein Concentrations
      IgG concentration 0.5 mg/ml
    • Reagents In The Kit
    • Preparing The Antibody
    • Test Principle
    • Buffer Solution
      TRIS buffered saline
    • Storage
      Store at +4oC or at -20oC if preferred.

      This product should be stored undiluted.

      Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use.
    • Shelf Life
      18 months from date of despatch.
    • GO Terms
      proteinaceous extracellular matrix
      extracellular space
      collagen catabolic process
      zinc ion binding
      metalloendopeptidase activity
      proteolysis
    • UniProt
    • Entrez Gene
    • Acknowledgements
    • Regulatory
      For research purposes only
    • This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

    • Application NameYesNoMin DilutionMax Dilution
      ELISA1/64000
      Western Blotting0.030.1ug/ml

    • Where this antibody has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. It is recommended that the user titrates the antibody for use in their own system using appropriate negative/positive controls.
    • Technical Advice
    • Recommended Protocol
    • ELISA
    • Immunohistology
    • Histology Positive Control Tissue
    • Immunofluorescence
    • Western Blotting
      AHP1081 detects a band of approximately 28kDa in human breast, ovary and placenta cell lysates. A minimum incubation time of 1 hour is recommended with this antibody.
    • Instructions For Use

    Additional MMP-7 Antibody Formats

    Formats Applications Sizes available
    MMP-7 Antibody : Purified E, WB 0.1 mg
    • Copyright © 2016 Bio-Rad

    Recommended Secondary Antibody

      DescriptionProduct CodePack SizeApplicationsList PriceQuantity
      Rabbit anti Goat IgG (Fc):FITCSTAR122F1 mgF
      STAR122F
      Rabbit anti Goat IgG (Fc):HRPSTAR122P1 mgC, E, WB
      STAR122P

      Recommended Negative Isotype Control

        Useful Reagents

          Recommended Positive Controls

            Histology Controls

              References

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