ACTH

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Synthetic Human ACTH (aa1-39)

Product Type: Antigen
Specificity: ACTH
Region: (aa1-39)

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Synthetic Human ACTH is a synthetic peptide corresponding to full-length mature human ACTH, a secreted hormone that stimulates the synthesis and release of corticosteroids from the adrenal cortex.

Target Species: Human
Product Form: Purified synthetic ACTH - liquid
Preparation: Solid phase synthesis
Buffer Solution: Trifluoroacetate salt
Preservative Stabilisers: None present
Purity: 98% by HPLC
Approx. Protein Concentrations: Total protein concentration 1.0 mg/ml
Protein Molecular Weight: 4,541 Da
Regulatory: For research purposes only
Guarantee: 12 months from date of despatch

Store at -20^oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.

This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.

Application Name	Verified	Min Dilution	Max Dilution
ELISA

Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.

Synonyms: Adrenocorticotropic Hormone
UniProt: P01189
Entrez Gene: POMC
GO Terms: GO:0005179 hormone activity; GO:0005615 extracellular space; GO:0030141 stored secretory granule; GO:0006091 generation of precursor metabolites and energy; GO:0007218 neuropeptide signaling pathway; GO:0007267 cell-cell signaling; GO:0008217 regulation of blood pressure; GO:0010552 positive regulation of gene-specific transcription from RNA polymerase II promoter; GO:0016486 peptide hormone processing; View More GO Terms; GO:0031781 type 3 melanocortin receptor binding; GO:0031782 type 4 melanocortin receptor binding; GO:0032098 regulation of appetite; GO:0032720 negative regulation of tumor necrosis factor production; GO:0033059 cellular pigmentation; GO:0034641 cellular nitrogen compound metabolic process; GO:0042446 hormone biosynthetic process; GO:0070996 type 1 melanocortin receptor binding