Human IgM Purified Immunoglobulin
- Product Type
- Purified Protein
|Human IgM Purified Immunoglobulin is purified IgM from myeloma serum. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-human serum and anti-human IgM (µ chain specific). No reaction was observed against anti-human IgG F(c). Some light chain cross reactivity will occur with human IgG.|
- Target Species
- Product Form
- Purified Protein - liquid
- Purified IgM prepared by delipidation, selective precipitation and tandem molecular sieve chromatography.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Approx. Protein Concentrations
- 1.0 mg/ml
- For research purposes only
- 12 months from date of despatch
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
|Application Name||Verified||Min Dilution||Max Dilution|
References for IgM
Litvack, M.L. et al. (2010) Natural IgM and innate immune collectin SP-D bind to late apoptotic cells and enhance their clearance by alveolar macrophages in vivo.
Mol Immunol.48: 37-47.
Cui, X. et al. (2016) Cytoplasmic myosin-exposed apoptotic cells appear with caspase-3 activation and enhance CLL cell viability.
Leukemia. 30 (1): 74-85.
Augé, E. et al. (2017) New perspectives on corpora amylacea in the human brain.
Sci Rep. 7: 41807.
Augé, E. et al. (2018) Astrocytes and neurons produce distinct types of polyglucosan bodies in Lafora disease.
Glia. 66 (10): 2094-107.
Riba, M. et al. (2019) Corpora amylacea act as containers that remove waste products from the brain.
Proc Natl Acad Sci U S A. 116 (51): 26038-48.
Riba, M. et al. (2022) Wasteosomes (corpora amylacea) of human brain can be phagocytosed and digested by macrophages.
Cell Biosci. 12 (1): 177.
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