IgM
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Human IgM Purified Immunoglobulin is purified IgM from myeloma serum. Assay by immunoelectrophoresis resulted in a single precipitin arc against anti-human serum and anti-human IgM (µ chain specific). No reaction was observed against anti-human IgG F(c). Some light chain cross reactivity will occur with human IgG.
Product Details
- Target Species
- Human
- Product Form
- Purified Protein - liquid
- Preparation
- Purified IgM prepared by delipidation, selective precipitation and tandem molecular sieve chromatography.
- Buffer Solution
- TRIS buffered saline
- Preservative Stabilisers
- 0.1% Sodium Azide (NaN3)
- Approx. Protein Concentrations
- 1.0 mg/ml
Storage Information
- Storage
- This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P01871
- Entrez Gene
- IGHM
- GO Terms
- GO:0003823 antigen binding
- GO:0016021 integral to membrane
- GO:0005624 membrane fraction
- Regulatory
- For research purposes only
Applications of IgM
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only.
Copyright © 2021 Bio-Rad Antibodies (formerly AbD Serotec)
Product Specific References
References for IgM
-
Litvack, M.L. et al. (2010) Natural IgM and innate immune collectin SP-D bind to late apoptotic cells and enhance their clearance by alveolar macrophages in vivo.
Mol Immunol.48: 37-47. -
Cui, X. et al. (2016) Cytoplasmic myosin-exposed apoptotic cells appear with caspase-3 activation and enhance CLL cell viability.
Leukemia. 30 (1): 74-85. -
Riba, M. et al. (2019) Corpora amylacea act as containers that remove waste products from the brain.
Proc Natl Acad Sci U S A. 116 (51): 26038-48. -
Augé, E. et al. (2017) New perspectives on corpora amylacea in the human brain.
Sci Rep. 7: 41807. -
Augé, E. et al. (2018) Astrocytes and neurons produce distinct types of polyglucosan bodies in Lafora disease.
Glia. 66 (10): 2094-107.
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