IgA
Purified Human Secretory IgA is derived from human colostrum and is predominately in dimeric form, the monomers being linked by immunoglobulin J chain.
Product Details
- Target Species
- Human
- Product Form
- Purified IgA - liquid
- Preparation
- Purified human secretory IgA prepared by size-exclusion and ion exchange chromatography.
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- Approx. Protein Concentrations
- 1.0 mg/ml
Storage Information
- Storage
- Store at -20oC only.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this product contain a precipitate we recommend microcentrifugation before use. - Guarantee
- 12 months from date of despatch
More Information
- UniProt
- P01876
- P01877
- Entrez Gene
- IGHA1
- IGHA2
- GO Terms
- GO:0005515 protein binding
- GO:0003823 antigen binding
- GO:0006955 immune response
- GO:0018298 protein-chromophore linkage
- GO:0005624 membrane fraction
- Regulatory
- For research purposes only
Applications of IgA
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
Copyright © 2021 Bio-Rad Antibodies (formerly AbD Serotec)
Product Specific References
References for IgA
-
Bidgood, S.R. et al. (2014) Translocalized IgA mediates neutralization and stimulates innate immunity inside infected cells.
Proc Natl Acad Sci U S A. 111 (37): 13463-8. -
Herrera, D. et al. (2013) Rotavirus specific plasma secretory immunoglobulin in children with acute gastroenteritis and children vaccinated with an attenuated human rotavirus vaccine.
Hum Vaccin Immunother. 9 (11): 2409-17. -
Zhang, J. et al. (2021) Role of Human Mesangial-Tubular Crosstalk in Secretory IgA-Induced IgA Nephropathy.
Kidney Blood Press Res. : Apr 161-12.
Fluorescent Spectraviewer
Watch the Tool Tutorial Video ▸How to Use the Spectraviewer
Watch the Tool Tutorial Video ▸- Start by selecting the application you are interested in, with the option to select an instrument from the drop down menu or create a customized instrument
- Select the fluorophores or fluorescent proteins you want to include in your panel to check compatibility
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