Filter by Application:E Reset
|Recombinant Bovine Interleukin-1 beta is a recombinant peptide corresponding to full-length mature Bovine Interleukin-1 beta (IL-1 beta) expressed by a number of cell types including monocytes, macrophages and endothelial cells.
Interleukin-1 beta, a pro-inflammatory cytokine has a wide range of effects, such as promoting T and B cell proliferation and inducing neutrophil chemotaxis.
- Target Species
- Species Cross-Reactivity
Target Species Cross Reactivity Mouse
- N.B. Antibody reactivity and working conditions may vary between species.
- Product Form
- Purified Recombinant Protein - lyophilized
- Reconstitute with 0.5 ml distilled water.
Further dilutions should be made in a buffer containing carrier protein.
Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. Bio-Rad recommend that the vial is gently mixed after reconstitution.
- Recombinant protein expressed in Pichia pastoris
- Buffer Solution
- Phosphate buffered saline
- Preservative Stabilisers
- None present
- >95% by SDS PAGE analysis
- Approx. Protein Concentrations
- 40ug/ml after reconstitution
- Protein Molecular Weight
- Endotoxin Level
- < 1.0 EU/ug
- For research purposes only
- 12 months from date of despatch
Following reconstitution store at -70oC.
Storage in frost-free freezers is not recommended.
This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.
|Application Name||Verified||Min Dilution||Max Dilution|
References for IL-1 Beta
Stradner, M.H. et al. (2008) Spingosine-1-phosphate stimulates proliferation and counteracts interleukin-1 induced nitric oxide formation in articular chondrocytes.
Osteoarthritis Cartilage. 16: 305-11.
Bougarn, S. et al. (2010) Muramyl dipeptide synergizes with Staphylococcus aureus lipoteichoic acid to recruit neutrophils in the mammary gland and to stimulate mammary epithelial cells.
Clin Vaccine Immunol. 17(11):1797-809.
Simojoki, H. et al. (2011) Innate immune response in experimentally induced bovine intramammary infection with Staphylococcus simulans and S. epidermidis.
Vet Res. 42: 49.
Vordermeier, M. et al. (2012) Cytokine responses of Holstein and Sahiwal zebu derived monocytes after mycobacterial infection.
Trop Anim Health Prod. 44: 651-5.
L, D. et al. (2015) Late production of CXCL8 in ruminant oro-nasal turbinate cells in response to Chlamydia abortus infection.
Vet Immunol Immunopathol. 168 (1-2): 97-102.
JA, C. et al. (2017) In utero exposure to LPS alters the postnatal acute-phase response in beef heifers.
Innate Immun. 23 (1): 97-108.
Always be the first to know.
When we launch new products and resources to help you achieve more in the lab.Yes, sign me up